MMP3 anticorps

N° du produit ABIN969539

2+ publications sont disponibles pour ce produit. L’anticorps anti-MMP3 Monoclonal produit chez le Souris a été validé pour ELISA et FACS. Il convient pour la détection de MMP3 dans des échantillons provenant de Humain. }

Aperçu rapide pour MMP3 anticorps (ABIN969539)

Antigène: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MMP3 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 4F10

Détail du produit anti-MMP3 anticorps

Fonction: MMP3 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human MMP3 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-MMP3 (ABIN969539)

Jin, Miao, Hu, Xu, Huang, Chen, Tian, Wei, Boffetta, Shen: "Putative functional polymorphisms of MMP9 predict survival of NSCLC in a Chinese population." dans: International journal of cancer. Journal international du cancer, Vol. 124, Issue 9, pp. 2172-8, (2009) (PubMed).

Nan, Niu, Hunter, Han: "Missense polymorphisms in matrix metalloproteinase genes and skin cancer risk." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3551-7, (2008) (PubMed).

Détails sur MMP3

Antigène: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Autre désignation: MMP3

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Poids moléculaire: 54 kDa

ID gène: 4314

UniProt: P08254