SOX9 anticorps

N° du produit ABIN969568

Cet anticorps Souris Monoclonal détecte spécifiquement SOX9 dans WB, ELISA et ICC. Il présente une réactivité envers Humain et a été mentionné dans 2+ publications.

Aperçu rapide pour SOX9 anticorps (ABIN969568)

Antigène: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOX9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Clone: 1B11

Détail du produit anti-SOX9 anticorps

Fonction: SOX9 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human SOX9 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-SOX9 (ABIN969568)

Dupasquier, Abdel-Samad, Glazer, Bastide, Jay, Joubert, Cavaillès, Blache, Quittau-Prévostel: "A new mechanism of SOX9 action to regulate PKCalpha expression in the intestine epithelium." dans: Journal of cell science, Vol. 122, Issue Pt 13, pp. 2191-6, (2009) (PubMed).

Gordon, Tan, Benko, Fitzpatrick, Lyonnet, Farlie: "Long-range regulation at the SOX9 locus in development and disease." dans: Journal of medical genetics, Vol. 46, Issue 10, pp. 649-56, (2009) (PubMed).

Détails sur SOX9

Antigène: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Autre désignation: SOX9

Sujet: The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Poids moléculaire: 56 kDa

ID gène: 6662

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development