FOLR1 anticorps
Aperçu rapide pour FOLR1 anticorps (ABIN99369)
Antigène
Voir toutes FOLR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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N° du produit (Fournisseur)
- 100-101-148
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Fournisseur
- Rockland
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Fonction
- Folate Binding Protein Antibody
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Réactivité croisée (Details)
- Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-goat serum, purified and partially purified Folate Binding Protein [Bovine Milk].
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Attributs du produit
- Synonyms: Folate receptor alpha, FR-alpha, Folate receptor 1, Milk folate-binding protein, Folate-binding protein 1, FBP, goat anti-folate binding protein antibody
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Purification
- This product was prepared from monospecific antiserum by a delipidation and defibrination.
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Immunogène
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Immunogen: Folate Binding Protein [Bovine Milk]
Immunogen Type: Native Protein
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Indications d'application
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Application Note: This product has been assayed against 1.0 μg of Folate Binding Protein [Bovine Milk] in a standard ELISA using Peroxidase conjugated Affinity Purified anti-Goat IgG [H&L] (Goat) code #611-1302 and (ABTS (2,2'-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) code # ABTS-100 as a substrate for 30 minutes at room temperature. A working dilution of 1:3,000 to 1:9,000 of the reconstitution concentration is suggested for this product.
Western Blot Dilution: 1:500 - 1:5,000
Immunoprecipitation Dilution: 1:100
ELISA Dilution: 1:5,000 - 1:20,000
Other: User Optimized
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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Reconstitution Volume: 2.0 mL
Reconstitution Buffer: Restore with deionized water (or equivalent)
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Concentration
- 90 mg/mL
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Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Date de péremption
- 12 months
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- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
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Autre désignation
- FOLR1
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Sujet
- Background: Folate Binding Protein binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. It has a high affinity for folate and folic acid analogs at neutral pH . Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. It is required for normal embryonic development and normal cell proliferation.
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ID gène
- 539750
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NCBI Accession
- NP_001193456
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UniProt
- P02702
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Pathways
- Dicarboxylic Acid Transport
Antigène
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