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ASAP1 Produits

(ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))
This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Catégories ASAP1 en vedette

ASAP1 Anticorps

High quality antibodies with extensive validation data.

ASAP1 Kits ELISA

Reliable ELISA kits for a wide range of species.

ASAP1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ASAP1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (5)
N° du produit ABIN565496
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
N° du produit ABIN753703
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Mouse
Application WB, ELISA, IHC
Validations
  • (1)
  • (1)
N° du produit ABIN129669
Quantité 100 μg
Fiche technique Fiche technique

ASAP1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6971241
Quantité 96 tests
Fiche technique Fiche technique

ASAP1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1345785
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3089560
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3137365
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ASAP1

Schreiber, Saraswati, Harkins, Gruber, Cremers, Thiele, Rothley, Plaumann, Korn, Armant, Augustin, Sleeman: "Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling." dans: PLoS genetics, Vol. 15, Issue 6, pp. e1008216, (2019) (PubMed).

Bender, Stritt, Nurden, van Eeuwijk, Zieger, Kentouche, Schulze, Morbach, Stegner, Heinze, Heinze, Dütting, Gupta, Witke, Falet, Fischer, Hartwig, Nieswandt: "Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect." dans: Nature communications, Vol. 5, pp. 4746, (2015) (PubMed).

Sato, Zhao, Imai, Simister, Feller, Trackman, Kirsch, Sonenshein: "Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide." dans: PLoS ONE, Vol. 8, Issue 10, pp. e77288, (2013) (PubMed).

Matsui, Kaieda, Ikegami, Mimori-Kiyosue: "Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF." dans: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 33006-20, (2008) (PubMed).

Liu, Yerushalmi, Grigera, Parsons: "Mislocalization or reduced expression of Arf GTPase-activating protein ASAP1 inhibits cell spreading and migration by influencing Arf1 GTPase cycling." dans: The Journal of biological chemistry, Vol. 280, Issue 10, pp. 8884-92, (2005) (PubMed).

Kruljac-Letunic, Moelleken, Kallin, Wieland, Blaukat: "The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1." dans: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 29560-70, (2003) (PubMed).

Liu, Loijens, Martin, Karginov, Parsons: "The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly." dans: Molecular biology of the cell, Vol. 13, Issue 6, pp. 2147-56, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à ASAP1

ArfGAP with SH3 domain, ankyrin repeat and PH domain1 (Asap1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1), toxic extracellular endopeptidase (asaP1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (Asap1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (asap1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog (asap1.L), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a (asap1a), AMAP1, ASAP1, Asap1, AV239055, CENTB4, Ddef1, DDEF1, ddef1, DEF-1, mKIAA1249, PAG2, PAP, s19, si:ch211-160i2.3, ZG14P

Protein level used designations for ASAP1

  • 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein
  • 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein
  • ADP-ribosylation factor-directed GTPase-activating protein 1
  • ARF GTPase-activating protein 1
  • PIP2-dependent ARF1 GAP
  • arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
  • development and differentiation-enhancing factor 1
  • DEF-1
  • centaurin, beta 4
  • development and differentiation enhancing factor 1
  • differentiation-enhancing factor 1
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
  • arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1-like
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain1
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
  • arfGAP with SH3 domain, ankyrin repeat and PH domain 1a
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