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ASIC3 Produits

(Amiloride-Sensitive Cation Channel 3 (ACCN3))

Catégories

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012].

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Catégories ASIC3 en vedette

ASIC3 Anticorps

High quality antibodies with extensive validation data.

ASIC3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ASIC3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7143004
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (2)
N° du produit ABIN202724
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN5571842
Quantité 100 μL
Fiche technique Fiche technique

ASIC3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121807
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3089253
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3123872
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ASIC3

Bychkov, Kirichenko, Shulepko, Mikhaylova, Kirpichnikov, Lyukmanova: "Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival Prognosis." dans: Biomedicines, Vol. 9, Issue 10, (2021) (PubMed).

Schuhmacher, Callejo, Srivats, Smith: "Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers." dans: The Journal of biological chemistry, Vol. 293, Issue 5, pp. 1756-1766, (2018) (PubMed).

Montalbetti, Rooney, Marciszyn, Carattino: "ASIC3 fine-tunes bladder sensory signaling." dans: American journal of physiology. Renal physiology, Vol. 315, Issue 4, pp. F870-F879, (2018) (PubMed).

Durham, Masterson: "Two mechanisms involved in trigeminal CGRP release: implications for migraine treatment." dans: Headache, Vol. 53, Issue 1, pp. 67-80, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à ASIC3

amiloride-sensitive cation channel 3 (ACCN3), acid sensing ion channel subunit 3 (ASIC3), acid sensing ion channel subunit 3 (Asic3), acid-sensing (proton-gated) ion channel 3 (Asic3), ACCN3, Accn3, AW742291, DRASIC, SLNAC1, TNaC1, TNAC1

Protein level used designations for ASIC3

  • amiloride-sensitive cation channel 3
  • amiloride-sensitive cation channel 3-like
  • DRASIC
  • acid sensing ion channel 3
  • acid-sensing ion channel 3
  • dorsal root ASIC
  • proton gated cation channel DRASIC
  • amiloride-sensitive cation channel 3, testis
  • modulatory subunit of ASIC2a
  • neuronal amiloride-sensitive cation channel 3
  • proton-gated cation channel subunit
  • testis sodium channel 1
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