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ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1A Protéines

(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1A (ABCB1A))

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a p-glycoprotein which actively transports a variety of hydrophobic amphipathic drugs and plays a major role in the blood-brain barrier permeability of certain drugs. [provided by RefSeq, Jul 2008].

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ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1A (ABCB1A) (AA 1-1276) protein (His tag)

custom-made ABCB1A Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Abcb1a Protein, UniprotID P21447

3 images

N° du produit ABIN7562958

Détails

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1A (ABCB1A) (AA 1-1276) protein (Strep Tag)

custom-made ABCB1A Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, SDS, WB

N° du produit ABIN3133296