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AXIN2 Protéines

(Axin 2 (AXIN2))

The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. [provided by RefSeq, Jul 2008].

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AXIN2 Protein (AA 1-840) (His tag)

custom-made AXIN2 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Axin2 Protein, UniprotID O88566

3 images

N° du produit ABIN7562630

Détails

AXIN2 Protein (AA 1-843) (His tag)

custom-made AXIN2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant AXIN2 Protein, UniprotID Q9Y2T1

3 images

N° du produit ABIN7552625

Détails

AXIN2 Protein (AA 579-843) (His tag)

AXIN2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA

Western Blotting (WB) image for Axin 2 (AXIN2) (AA 579-843) protein (His tag) (ABIN7121955)

1 image

N° du produit ABIN7121955

Détails

AXIN2 Protein (AA 1-160) (GST tag)

AXIN2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP

Image no. 1 for Axin 2 (AXIN2) (AA 1-160) protein (GST tag) (ABIN1346239)

1 image

N° du produit ABIN1346239

Détails

AXIN2 Protein (AA 350-631) (His tag)

AXIN2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, PC, Imm

N° du produit ABIN7396028

Détails

AXIN2 Protein (AA 1-840) (Strep Tag)

custom-made AXIN2 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3132149

Détails

AXIN2 Protein (AA 1-843) (Strep Tag)

custom-made AXIN2 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3089867