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BACE1 Protéines

(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].

23 Résultats

BACE1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7273905
 
BACE1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7273906
 
BACE1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7121998
 
BACE1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
N° du produit ABIN1346345
 
BACE1 Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7491349
 
BACE1 Origine: Souris Hôte: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
N° du produit ABIN7320444
 
BACE1 Origine: Humain Hôte: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE.
Pubmed 2 références
N° du produit ABIN2180626
 
BACE1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505103
 
BACE1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
N° du produit ABIN7391801
 
BACE1 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
N° du produit ABIN7411204
 
BACE1 Origine: Humain Hôte: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. WB, SDS, Imm, ELISA, AcA Active
N° du produit ABIN7607491
 
BACE1 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
N° du produit ABIN7391804
 
BACE1 Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
N° du produit ABIN7391807
 
BACE1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
N° du produit ABIN7318053
 
BACE1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
N° du produit ABIN7318054
 
BACE1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
N° du produit ABIN7318055
 
BACE1 Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS, EAA Active
N° du produit ABIN7596290
 
BACE1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % Inactive
N° du produit ABIN7668233
 
BACE1 Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
N° du produit ABIN3008460
 
BACE1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2715129
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Enzyme Activity Assay (EAA)
    • Immunoprecipitation (IP)
    • Standard (STD)
  • Réactivité
    • Human
    • Mouse
    • Rat
    • Cow
    • Guinea Pig
  • Cité dans publications
  • Images disponible
  • Carrier free only
  • Hote
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Yeast
    • Baculovirus infected Insect Cells
    • Mammalian Cells
    • Wheat germ
  • Epitope
    • AA 22-457
    • AA 170-428
    • AA 181-366
    • AA 190-430
    • AA 22-429
    • AA 22-460
    • AA 22-501
    • AA 46-152
    • Transcript Variant A
  • Conjugué
    • His tag
    • Inconjugué
    • Fc Tag
    • His tag,GST tag
    • GST tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Type Proteine
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Activité biologique
    • Biologically Active
    • Biologically Inactive
  • Supplier
    • antibodies-online
    • CUSABIO
    • ACROBiosystems
    • Abbexa
    • OriGene

Dernières publications pour nos BACE1 Protéines

Mycroft-West, Devlin, Cooper, Procter, Miller, Fernig, Guerrini, Guimond, Lima, Yates, Skidmore: "Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus." dans: Neural regeneration research, Vol. 15, Issue 8, pp. 1546-1553, (2020) (PubMed).

Peters-Libeu, Campagna, Mitsumori, Poksay, Spilman, Sabogal, Bredesen, John: "sAβPPα is a Potent Endogenous Inhibitor of BACE1." dans: Journal of Alzheimer's disease : JAD, Vol. 47, Issue 3, pp. 545-55, (2015) (PubMed).

Pseudonymes pour BACE1 Protéines

beta-secretase 1 (BACE1) Protéines
beta-site APP cleaving enzyme 1 (Bace1) Protéines
beta-secretase 1 (Bace1) Protéines
beta-site APP-cleaving enzyme 1 (bace1) Protéines
ASP2 Protéines
BACE Protéines
Bace Protéines
BACE1 Protéines
C76936 Protéines
HSPC104 Protéines
MGC145931 Protéines
zgc:77409 Protéines
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