BACE1 Protéines
(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].
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22 Résultats
BACE1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Active
BACE1
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Active
BACE1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
BACE1
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
BACE1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
AM, ADA, IA, ScA
1 image
BACE1
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 97 % as determined by SDS-PAGE
Active
1 image
BACE1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>98 % as determined by SDS-PAGE.
1 image
2 références
BACE1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
BACE1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
BACE1
Origine: Humain
Hôte: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
BACE1
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
BACE1
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
BACE1
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 %
SDS, EAA
Active
BACE1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
BACE1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
BACE1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
Active
BACE1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
Inactive
BACE1
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
BACE1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Dernières publications pour nos BACE1 Protéines
: "Inhibition of BACE1, the β-secretase implicated in Alzheimer's disease, by a chondroitin sulfate extract from Sardina pilchardus." dans: Neural regeneration research, Vol. 15, Issue 8, pp. 1546-1553, (2020) (PubMed).: "sAβPPα is a Potent Endogenous Inhibitor of BACE1." dans: Journal of Alzheimer's disease : JAD, Vol. 47, Issue 3, pp. 545-55, (2015) (PubMed).
Pseudonymes pour BACE1 Protéines
beta-secretase 1 (BACE1) Protéinesbeta-site APP cleaving enzyme 1 (Bace1) Protéines
beta-secretase 1 (Bace1) Protéines
beta-site APP-cleaving enzyme 1 (bace1) Protéines
ASP2 Protéines
BACE Protéines
Bace Protéines
BACE1 Protéines
C76936 Protéines
HSPC104 Protéines
MGC145931 Protéines
zgc:77409 Protéines
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