CAD Produits
(Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
Catégories
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. [provided by RefSeq, Jul 2008].
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Catégories CAD en vedette
CAD Anticorps
High quality antibodies with extensive validation data.
CAD recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (7)
N° du produit
ABIN655062
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (8)
N° du produit
ABIN7264367
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
N° du produit
ABIN6137837
Quantité
100 μL
Fiche technique
Fiche technique
CAD recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122124
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CAD
: "Identification of CAD as an androgen receptor interactant and an early marker of prostate tumor recurrence." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 1, pp. 460-7, (2012) (PubMed).: "Phospho-ΔNp63α/SREBF1 protein interactions: bridging cell metabolism and cisplatin chemoresistance." dans: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 20, pp. 3810-27, (2012) (PubMed).
: "Expression of caspase-activated deoxyribonuclease (CAD) and caspase 3 (CPP32) in the cochlea of cisplatin (CDDP)-treated guinea pigs." dans: Auris, nasus, larynx, Vol. 30, Issue 3, pp. 219-25, (2003) (PubMed).
: "Expression of caspase-activated deoxyribonuclease (CAD) and caspase 3 (CPP32) in the hydropic cochlea of guinea pigs - second report." dans: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, Vol. 259, Issue 5, pp. 257-61, (2002) (PubMed).
: "Over expression of inhibitor of caspase 3 activated deoxyribonuclease in human renal cell carcinoma cells enhances their resistance to cytotoxic chemotherapy in vivo." dans: The Journal of urology, Vol. 166, Issue 6, pp. 2491-4, (2001) (PubMed).
: "TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB." dans: Immunity, Vol. 7, Issue 6, pp. 831-6, (1998) (PubMed).
Synonymes et noms alternatifs relatifs à CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD), carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (Cad), carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (cad), 2410008J01Rik, AU018859, CAD, cb456, Cpad, si:dkey-221h15.3, wu:fc30c12, wu:fc33d01, wu:fc67g02, xcadProtein level used designations for CAD
- CAD protein
- CAD trifunctional protein
- multifunctional protein CAD
- carbamyl phosphatate synthetase 2
- carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase
- carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
- CAD protein-like
- CAD protein carbamylphosphate synthetase domain
- dihydrorotate synthase
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