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CARD16 Protéines

(Caspase Recruitment Domain Family, Member 16 (CARD16))

Caspase inhibitor. Acts as a regulator of procaspase- 1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro- inflammatory cytokine response. Also able to inhibit CASP1- mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

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CARD16 Protein (AA 1-197) (His tag)

custom-made CARD16 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant CARD16 Protein, UniprotID Q5EG05

3 images

N° du produit ABIN7552897

Détails

CARD16 Protein (AA 1-97) (GST tag)

CARD16 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP

Image no. 1 for Caspase Recruitment Domain Family, Member 16 (CARD16) (AA 1-97) protein (GST tag) (ABIN1348045)

1 image

N° du produit ABIN1348045

Détails

CARD16 Protein (AA 1-197) (Strep Tag)

custom-made CARD16 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3090483