CASR Produits
(Calcium-Sensing Receptor (CASR))
Catégories
The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008].
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Catégories CASR en vedette
CASR Anticorps
High quality antibodies with extensive validation data.
CASR Kits ELISA
Reliable ELISA kits for a wide range of species.
CASR Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CASR recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (1)
- (4)
N° du produit
ABIN1678994
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (4)
N° du produit
ABIN6255749
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Pig
Application
WB, ELISA
Validations
- (2)
- (2)
N° du produit
ABIN1386858
Quantité
100 μL
Fiche technique
Fiche technique
CASR recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6954279
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6954278
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6954280
Quantité
96 tests
Fiche technique
Fiche technique
CASR recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348127
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348129
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3090657
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CASR
: "Activation of the calcium-sensing receptor in human valvular interstitial cells promotes calcification." dans: Journal of molecular and cellular cardiology, Vol. 129, pp. 2-12, (2019) (PubMed).: "Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro." dans: Cell stem cell, Vol. 25, Issue 2, pp. 225-240.e7, (2019) (PubMed).
: "Immunolocalization of calcium sensing and transport proteins in the murine endolymphatic sac indicates calciostatic functions within the inner ear." dans: Cell and tissue research, (2019) (PubMed).
: "Involvement of calcium-sensing receptor activation in the alleviation of intestinal inflammation in a piglet model by dietary aromatic amino acid supplementation." dans: The British journal of nutrition, Vol. 120, Issue 12, pp. 1321-1331, (2019) (PubMed).
: "Calcium-sensing receptor (CaSR) promotes development of bone metastasis in renal cell carcinoma." dans: Oncotarget, Vol. 9, Issue 21, pp. 15766-15779, (2018) (PubMed).
: "Evaluation of a TPTX model induced by ischemia." dans: Experimental animals, Vol. 66, Issue 4, pp. 345-356, (2018) (PubMed).
: "Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin ..." dans: Oncotarget, Vol. 8, Issue 34, pp. 56460-56472, (2017) (PubMed).
: "Involvement of the calcium-sensing receptor in mineral trioxide aggregate-induced osteogenic gene expression in murine MC3T3-E1 cells." dans: Dental materials journal, Vol. 36, Issue 4, pp. 469-475, (2017) (PubMed).
: "Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension." dans: Hypertension (Dallas, Tex. : 1979), Vol. 69, Issue 5, pp. 844-854, (2017) (PubMed).
: "Monocrotaline Induces Endothelial Injury and Pulmonary Hypertension by Targeting the Extracellular Calcium-Sensing Receptor." dans: Journal of the American Heart Association, Vol. 6, Issue 4, (2017) (PubMed).
Synonymes et noms alternatifs relatifs à CASR
calcium sensing receptor (CASR), calcium-sensing receptor (Casr), calcium-sensing receptor L homeolog (casr.L), calcium sensing receptor (Casr), CAR, CaR, CASR, EIG8, FHH, FIH, GPRC2A, Gprc2a, gprc2a, HHC, HHC1, HYPOC1, NSHPT, PCAR1, xV2R F-1Protein level used designations for CASR
- extracellular calcium-sensing receptor
- parathyroid Ca(2+)-sensing receptor 1
- parathyroid cell calcium-sensing receptor
- G protein coupled receptor, family C, group 2, member A
- G protein-coupled receptor, family C, group 2, member A
- PCaR1
- cation sensing receptor
- Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism)
- Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)
- parathyroid Cell calcium-sensing receptor
- calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism)
- calcium-sensing receptor
- vomeronasal receptor F-1
- parathyroid gland calcium-sensing receptor
- extracellular calcium-sensing receptor-like
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