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C1q Produits

(Complement Fragment C1q (C1q))
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

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Catégories C1q en vedette

C1q Anticorps

High quality antibodies with extensive validation data.

C1q Kits ELISA

Reliable ELISA kits for a wide range of species.

C1q Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

C1q recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application IHC (fro)
Validations
  • (3)
N° du produit ABIN2477784
Quantité 1 mL
Fiche technique Fiche technique
Reactivity Mouse
Application FACS, IHC (fro), IF, Func
Validations
  • (3)
N° du produit ABIN2191846
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Mouse
Application FACS, IA
Validations
  • (5)
N° du produit ABIN2191787
Quantité 100 μg
Fiche technique Fiche technique

C1q recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
N° du produit ABIN6955043
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Monkey
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6963095
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6999543
Quantité 96 tests
Fiche technique Fiche technique

C1q recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source
Validations
N° du produit ABIN1062256
Quantité 200 μg
Fiche technique Fiche technique

Dernières publications sur nos produits C1q

Silva-Cardoso, Tao, Fernández, Boes, Radstake, Pandit: "CXCL4 suppresses tolerogenic immune signature of monocyte-derived dendritic cells." dans: European journal of immunology, Vol. 50, Issue 10, pp. 1598-1601, (2021) (PubMed).

Huang, Cui, Gu, Zhang, Qu, Wang, Wang, Cheng, Meng, Liu, Zhao: "Complement activation profile of patients with primary focal segmental glomerulosclerosis." dans: PLoS ONE, Vol. 15, Issue 6, pp. e0234934, (2020) (PubMed).

Sikora, Wróblewska-Czech, Smycz-Kubańska, Mielczarek-Palacz, Cygal, Witek, Kondera-Anasz: "The role of complement components C1q, MBL and C1 inhibitor in pathogenesis of endometriosis." dans: Archives of gynecology and obstetrics, Vol. 297, Issue 6, pp. 1495-1501, (2018) (PubMed).

Eriksson, Studahl, Bergström: "Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis." dans: Journal of neuroimmunology, Vol. 295-296, pp. 130-8, (2016) (PubMed).

Ma, Cui, Liao, Zhao: "Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease." dans: Journal of clinical immunology, Vol. 33, Issue 1, pp. 172-8, (2013) (PubMed).

Neiman, Fredolini, Johansson, Lehtiö, Nygren, Uhlén, Nilsson, Schwenk: "Selectivity analysis of single binder assays used in plasma protein profiling." dans: Proteomics, Vol. 13, Issue 23-24, pp. 3406-10, (2013) (PubMed).

Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: "Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model." dans: Proteome science, Vol. 9, pp. 73, (2011) (PubMed).

Erlich, Dumestre-Pérard, Ling, Lemaire-Vieille, Schoehn, Arlaud, Thielens, Gagnon, Cesbron: "Complement protein C1q forms a complex with cytotoxic prion protein oligomers." dans: The Journal of biological chemistry, Vol. 285, Issue 25, pp. 19267-76, (2010) (PubMed).

Castellano, Melchiorre, Loverre, Ditonno, Montinaro, Rossini, Divella, Battaglia, Lucarelli, Annunziata, Palazzo, Selvaggi, Staffieri, Crovace, Daha, Mannesse, van Wetering, Paolo Schena, Grandaliano: "Therapeutic targeting of classical and lectin pathways of complement protects from ischemia-reperfusion-induced renal damage." dans: The American journal of pathology, Vol. 176, Issue 4, pp. 1648-59, (2010) (PubMed).

Ankeny, Guan, Popovich: "B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice." dans: The Journal of clinical investigation, Vol. 119, Issue 10, pp. 2990-9, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à C1q

complement component 1, q subcomponent, alpha polypeptide (C1qa), AI255395, C1q

Protein level used designations for C1q

  • complement C1q subcomponent subunit A
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