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CCR3 Produits

(Chemokine (C-C Motif) Receptor 3 (CCR3))
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009].

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Catégories CCR3 en vedette

CCR3 Anticorps

High quality antibodies with extensive validation data.

CCR3 Kits ELISA

Reliable ELISA kits for a wide range of species.

CCR3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CCR3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC, Neut
Validations
  • (5)
N° du produit ABIN5611257
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (4)
N° du produit ABIN738651
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7145926
Quantité 100 μg
Fiche technique Fiche technique

CCR3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965709
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954648
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5593527
Quantité 96 tests
Fiche technique Fiche technique

CCR3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348497
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3098499
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3134377
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CCR3

Lei, Zeng, Liu, Zhu, Wang, Wu, Jiang, Huang: "Crucial role of OX40/OX40L signaling in a murine model of asthma." dans: Molecular medicine reports, Vol. 17, Issue 3, pp. 4213-4220, (2018) (PubMed).

Ge, Ha, Greenberg, Rao, Bastan, Blidner, Rao, Rabinovich, Sriramarao: "Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 33, pp. E4837-46, (2016) (PubMed).

Chen, Wang, Nelson, Tian, Mulvey, Patel, Conti, Jaen, Rollins: "CCL2/CCR2 Regulates the Tumor Microenvironment in HER-2/neu-Driven Mammary Carcinomas in Mice." dans: PLoS ONE, Vol. 11, Issue 11, pp. e0165595, (2016) (PubMed).

Kämpfer, Odermatt, Dahinden, Fux: "Late IL-3-induced phenotypic and functional alterations in human basophils require continuous IL-3 receptor signaling." dans: Journal of leukocyte biology, Vol. 101, Issue 1, pp. 227-238, (2016) (PubMed).

Williams, José, Mercer, Brealey, Parekh, Thickett, OKane, McAuley, Chambers: "Evidence for chemokine synergy during neutrophil migration in ARDS." dans: Thorax, Vol. 72, Issue 1, pp. 66-73, (2016) (PubMed).

Tian, Chen, Ma, Wang, Shao, Wu, Wu, Jin: "Expression and prognostic significance of CCL11/CCR3 in glioblastoma." dans: Oncotarget, Vol. 7, Issue 22, pp. 32617-27, (2016) (PubMed).

Huang, Tao, Shen, Chen: "Hypoxia induced CCL28 promotes angiogenesis in lung adenocarcinoma by targeting CCR3 on endothelial cells." dans: Scientific reports, Vol. 6, pp. 27152, (2016) (PubMed).

Fu, Tsai, Lee, Huang, Chang, Su Pang: "Simvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary Eosinophils." dans: PLoS ONE, Vol. 11, Issue 6, pp. e0157186, (2016) (PubMed).

Schollaert, Stephens, Gray, Fulkerson: "Generation of eosinophils from cryopreserved murine bone marrow cells." dans: PLoS ONE, Vol. 9, Issue 12, pp. e116141, (2015) (PubMed).

Takeda, Shiraishi, Ashino, Han, Jia, Wang, Lee, Lee, Gelfand: "Eosinophils contribute to the resolution of lung-allergic responses following repeated allergen challenge." dans: The Journal of allergy and clinical immunology, Vol. 135, Issue 2, pp. 451-60, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à CCR3

C-C motif chemokine receptor 3 (CCR3), chemokine (C-C motif) receptor 3 (Ccr3), C-C motif chemokine receptor 3 (Ccr3), CC-CKR-3, CC-CKR3, CD193, CKR3, Cmkbr1l2, CMKBR3, Cmkbr3

Protein level used designations for CCR3

  • C-C CKR-3
  • C-C chemokine receptor type 3
  • CC chemokine receptor 3
  • CCR-3
  • b-chemokine receptor
  • eosinophil CC chemokine receptor 3
  • eosinophil eotaxin receptor
  • CC-CKR-3
  • MIP-1 alpha RL2
  • MIP-1 alphaRL2
  • chemokine (C-C) receptor 1,-like 2
  • chemokine (C-C) receptor 3
  • macrophage inflammatory protein 1-alpha receptor-like 2
  • probable C-C chemokine receptor type 3
  • CKR3
  • C-C chemokine receptor 3
  • eotaxin receptor CCR3
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