CD137 Produits
(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
Catégories
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008].
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Catégories CD137 en vedette
CD137 Anticorps
High quality antibodies with extensive validation data.
CD137 Kits ELISA
Reliable ELISA kits for a wide range of species.
CD137 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CD137 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, FACS, WB, IHC (p)
Validations
- (2)
- (1)
- (1)
N° du produit
ABIN740445
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, FACS, WB, IHC, IF, IHC (p), Coat, StM
Validations
- (8)
N° du produit
ABIN6939788
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, FACS
Validations
- (5)
N° du produit
ABIN7092873
Quantité
100 μg
Fiche technique
Fiche technique
CD137 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6970994
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960300
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN924754
Quantité
96 tests
Fiche technique
Fiche technique
CD137 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7273924
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7273922
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7273923
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CD137
: "4-1BB Signaling Promotes Alveolar Macrophages-Mediated Pro-Fibrotic Responses and Crystalline Silica-Induced Pulmonary Fibrosis in Mice." dans: Frontiers in immunology, Vol. 9, pp. 1848, (2019) (PubMed).: "Anti-CD137 monoclonal antibody enhances trastuzumab-induced, natural killer cell-mediated cytotoxicity against pancreatic cancer cell lines with low human epidermal growth factor-like receptor 2 ..." dans: PLoS ONE, Vol. 13, Issue 12, pp. e0200664, (2018) (PubMed).
: "Decreased beige adipocyte number and mitochondrial respiration coincide with increased histone methyl transferase (G9a) and reduced FGF21 gene expression in Sprague-Dawley rats fed prenatal low ..." dans: The Journal of nutritional biochemistry, Vol. 31, pp. 113-21, (2016) (PubMed).
: "Isoproterenol Increases Uncoupling, Glycolysis, and Markers of Beiging in Mature 3T3-L1 Adipocytes." dans: PLoS ONE, Vol. 10, Issue 9, pp. e0138344, (2016) (PubMed).
: "Targeting peripheral blood pro-inflammatory cytotoxic lymphocytes by inhibiting CD137 expression: novel potential treatment for COPD." dans: BMC pulmonary medicine, Vol. 14, pp. 85, (2015) (PubMed).
: "Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development." dans: Cell death and differentiation, (2014) (PubMed).
: "Human and mouse CD137 have predominantly different binding CRDs to their respective ligands." dans: PLoS ONE, Vol. 9, Issue 1, pp. e86337, (2014) (PubMed).
: "SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line." dans: International journal of oncology, Vol. 41, Issue 4, pp. 1486-94, (2013) (PubMed).
: "T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 12, pp. 6694-706, (2013) (PubMed).
: "CD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis." dans: Immunology and cell biology, Vol. 90, Issue 4, pp. 449-56, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à CD137
tumor necrosis factor receptor superfamily member 9 (TNFRSF9), TNF receptor superfamily member 9 (TNFRSF9), tumor necrosis factor receptor superfamily, member 9a (tnfrsf9a), tumor necrosis factor receptor superfamily, member 9 (Tnfrsf9), 4-1BB, A930040I11Rik, AA408498, AI325004, CD137, Cd137, CDw137, ILA, Ly63, TNFRSF9, zgc:136557Protein level used designations for CD137
- tumor necrosis factor receptor superfamily, member 9
- tumor necrosis factor receptor superfamily member 9
- 4-1BB ligand receptor
- CD137 antigen
- T cell antigen ILA
- T-cell antigen 4-1BB homolog
- T-cell antigen ILA
- homolog of mouse 4-1BB
- induced by lymphocyte activation (ILA)
- interleukin-activated receptor, homolog of mouse Ly63
- receptor protein 4-1BB
- T-cell antigen 4-1BB
- secreted CD137 antigen
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