The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012].
Pierog, Krishna, Yamniuk, Chauhan, DeSilva: "Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples." dans: Journal of immunological methods, Vol. 416, pp. 124-36, (2015) (PubMed).
Pseudonymes pour CD16 Protéines
Fc fragment of IgG, low affinity IIa, receptor (Fcgr2a) Protéines Fc fragment of IgG, low affinity IIIa, receptor (CD16a) (FCGR3A) Protéines Fc fragment of IgG receptor IIIb (FCGR3B) Protéines Fc fragment of IgG receptor IIIa (FCGR3A) Protéines Fc receptor, IgG, low affinity III (Fcgr3) Protéines Fc-gamma RIII (FCGR3) Protéines CD16 Protéines CD16b Protéines FCG3 Protéines Fcgr3 Protéines FCGR3 Protéines FCGR3@ Protéines Fcgr3a Protéines FCR-10 Protéines FCRIII Protéines FcRIII Protéines FCRIIIb Protéines