CD276 Protéines
(CD276)
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
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CD276
Origine: Humain
Hôte: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
CD276
Origine: Humain
Hôte: Human Cells
Recombinant
CD276
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 97 % by SDS-PAGE.
Active
CD276
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % by SDS-PAGE.
Active
CD276
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 92 % by SDS-PAGE.
Active
CD276
Origine: Humain
Hôte: CHO Cells
Recombinant
>98 % (SDS-PAGE)
Active
CD276
Origine: Souris
Hôte: CHO Cells
Recombinant
>98 % (SDS-PAGE)
CD276
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
Active
CD276
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Active
CD276
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Active
CD276
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Active
CD276
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>95 % , as determined by SDS-PAGE and HPLC
CD276
Origine: Souris
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 %
SDS
Dernières publications pour nos CD276 Protéines
: "B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression." dans: Cell death & disease, Vol. 11, Issue 1, pp. 55, (2020) (PubMed).
: "Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276." dans: ACS combinatorial science, Vol. 21, Issue 3, pp. 207-222, (2020) (PubMed).
: "Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells." dans: Cancer cell, Vol. 35, Issue 2, pp. 221-237.e8, (2019) (PubMed).
: "Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer." dans: The Journal of experimental medicine, Vol. 216, Issue 4, pp. 982-1000, (2019) (PubMed).
: "Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276." dans: ACS combinatorial science, Vol. 21, Issue 3, pp. 207-222, (2020) (PubMed).
: "Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells." dans: Cancer cell, Vol. 35, Issue 2, pp. 221-237.e8, (2019) (PubMed).
: "Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer." dans: The Journal of experimental medicine, Vol. 216, Issue 4, pp. 982-1000, (2019) (PubMed).
Pseudonymes pour CD276 Protéines
CD276 molecule (CD276) ProtéinesCD276 molecule S homeolog (cd276.S) Protéines
CD276 molecule (cd276) Protéines
CD276 antigen (Cd276) Protéines
Cd276 molecule (Cd276) Protéines
4Ig-B7-H3 Protéines
6030411F23Rik Protéines
AU016588 Protéines
B7-H3 Protéines
B7h3 Protéines
B7H3 Protéines
B7RP-2 Protéines
sc:d0645 Protéines
zgc:158279 Protéines
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