CDK4 Protéines
(Cyclin-Dependent Kinase 4 (CDK4))
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
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CDK4
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
1 reference
CDK4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
CDK4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
CDK4
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
CDK4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Imm
CDK4
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 80 % as determined by reducing SDS-PAGE.
CDK4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
CDK4
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
CDK4
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
Inactive
CDK4
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
CDK4
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
CDK4
Origine: Xenopus laevis
Hôte: Levure
Recombinant
> 90 %
ELISA
Dernières publications pour nos CDK4 Protéines
: "Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"." dans: Molecular and cellular biology, Vol. 26, Issue 13, pp. 5070-85, (2006) (PubMed).Pseudonymes pour CDK4 Protéines
cyclin-dependent kinase 4 (cdk4) Protéinescyclin dependent kinase 4 (CDK4) Protéines
cyclin-dependent kinase 4 (Cdk4) Protéines
cyclin dependent kinase 4 (Cdk4) Protéines
Cyclin-dependent kinase 4 (Cdk4) Protéines
cyclin-dependent kinase 4 L homeolog (cdk4.L) Protéines
8-6 Protéines
cdk Protéines
CDK4 Protéines
cdk4 Protéines
CDK4/6 Protéines
Cdk4/6 Protéines
cdk4/6 Protéines
CG5072 Protéines
CMM3 Protéines
Crk3 Protéines
dCdk4 Protéines
DmCdk4 Protéines
Dmel\\CG5072 Protéines
l(2)05428 Protéines
l(2)0671 Protéines
l(2)k06503 Protéines
l(2)s4639 Protéines
l(2)sh0671 Protéines
Pk53C Protéines
Pk?7 Protéines
PSK-J3 Protéines
xcdk4 Protéines
zgc:153726 Protéines
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