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CKAP5 Produits

(Cytoskeleton Associated Protein 5 (CKAP5))

Catégories

This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation\; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].

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Catégories CKAP5 en vedette

CKAP5 Anticorps

High quality antibodies with extensive validation data.

CKAP5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IP, IF
Validations
  • (5)
N° du produit ABIN6138647
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (4)
N° du produit ABIN7149368
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Chicken, Chimpanzee, Cow, Dog, Frog, Human, Mouse, Opossum, Rat
Application WB, IP, IF
Validations
  • (2)
N° du produit ABIN5575372
Quantité 100 μL
Fiche technique Fiche technique

CKAP5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7421719
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CKAP5

Milunovic-Jevtic, Jevtic, Levy, Gatlin: "In vivo mitotic spindle scaling can be modulated by changing the levels of a single protein: the microtubule polymerase XMAP215." dans: Molecular biology of the cell, Vol. 29, Issue 11, pp. 1311-1317, (2018) (PubMed).

Kourtidis, Anastasiadis: "PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications." dans: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 4, pp. 498-505, (2016) (PubMed).

Dionne, Sanchez, Compton: "ch-TOGp is required for microtubule aster formation in a mammalian mitotic extract." dans: The Journal of biological chemistry, Vol. 275, Issue 16, pp. 12346-52, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à CKAP5

cytoskeleton associated protein 5 (ckap5), cytoskeleton associated protein 5 S homeolog (ckap5.S), cytoskeleton associated protein 5 (CKAP5), cytoskeleton-associated protein 5 (LOC100548902), cytoskeleton associated protein 5 (Ckap5), 3110043H24Rik, 4930432B04Rik, ch-TOG, CHTOG, ckap5, CKAP5, ckap5b, D730027C18Rik, im:7143385, mKIAA0097, msps, MSPS, T25636, tog, TOG, togp, TOGp, wu:fb14c01, wu:fb59e03, wu:fi33f02, xmap215, zgc:123012

Protein level used designations for CKAP5

  • cytoskeleton associated protein 5
  • microtubule associated protein XMAP215
  • cytoskeleton-associated protein 5
  • microtubule-associated protein 215
  • colonic and hepatic tumor over-expressed protein
  • Cytoskeleton-associated protein 5
  • cytoskeleton-associated protein 5-like
  • colonic and hepatic tumor over-expressed gene protein
  • colonic and hepatic tumor overexpressed gene protein
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