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Coagulation Factor X Produits

(Coagulation Factor X (F10))
This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds\; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq, Jul 2008].

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Catégories Coagulation Factor X en vedette

Coagulation Factor X Anticorps

High quality antibodies with extensive validation data.

Coagulation Factor X Kits ELISA

Reliable ELISA kits for a wide range of species.

Coagulation Factor X Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Coagulation Factor X recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (5)
N° du produit ABIN7432706
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
N° du produit ABIN390688
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (3)
N° du produit ABIN2856706
Quantité 100 μL
Fiche technique Fiche technique

Coagulation Factor X recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6954878
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965901
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965903
Quantité 96 tests
Fiche technique Fiche technique

Coagulation Factor X recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1353291
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Human Cells
Validations
  • (1)
N° du produit ABIN7320491
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3079915
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Coagulation Factor X

Posthuma, Posma, van Oerle, Leenders, van Gorp, Jaminon, Mackman, Heitmeier, Schurgers, Ten Cate, Spronk: "Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice." dans: Scientific reports, Vol. 9, Issue 1, pp. 3909, (2019) (PubMed).

Wang, Braun, Zhang, Norström, Thorlacius: "Thrombin generation in abdominal sepsis is Rho-kinase-dependent." dans: Biochemical and biophysical research communications, Vol. 460, Issue 3, pp. 691-6, (2015) (PubMed).

Wang, Braun, Zhang, Norström, Thorlacius: "Monocytes regulate systemic coagulation and inflammation in abdominal sepsis." dans: American journal of physiology. Heart and circulatory physiology, Vol. 308, Issue 5, pp. H540-7, (2015) (PubMed).

Khare, Hillestad, Xu, Byrnes, Barry: "Circulating antibodies and macrophages as modulators of adenovirus pharmacology." dans: Journal of virology, Vol. 87, Issue 7, pp. 3678-86, (2013) (PubMed).

Sudduth, Powell, Smith, Greenstein, Wilcock: "Induction of hyperhomocysteinemia models vascular dementia by induction of cerebral microhemorrhages and neuroinflammation." dans: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 5, pp. 708-15, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à Coagulation Factor X

coagulation factor X (F10), coagulation factor X (f10), coagulation factor X (CpipJ_CPIJ012712), coagulation factor X (CpipJ_CPIJ014863), coagulation factor X (CpipJ_CPIJ016937), coagulation factor X (CpipJ_CPIJ017791), Coagulation factor X (fa10), coagulation factor 10 L homeolog (f10.L), Cf10, F10, f10, fi12c10, FX, fX, FXA, wu:fi12c10

Protein level used designations for Coagulation Factor X

  • Stuart-Prower factor
  • factor Xa
  • prothrombinase
  • stuart factor
  • coagulation factor 10
  • VAP
  • factor XA light chain
  • virus activating protease
  • virus-activating protease
  • coagulation factor X
  • vitamin K dependent serine protease
  • coagulation factor X preproprotein
  • blood coagulation factor X
  • Coagulation factor X
  • coagulation factor 10 L homeolog
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