COMP Protéines
(Cartilage Oligomeric Matrix Protein (COMP))
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2008].
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18 Résultats
COMP
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
COMP
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
COMP
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, Imm, PC
COMP
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS, WB, Imm, PC
COMP
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
COMP
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
COMP
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
COMP
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
COMP
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 97 %
SDS, WB, Imm, PC
COMP
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
COMP
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 85 % by SDS - PAGE
SDS
COMP
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
Inactive
COMP
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, ELISA, IP
1 image
COMP
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Dernières publications pour nos COMP Protéines
: "ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas." dans: FEBS open bio, Vol. 10, Issue 9, pp. 1856-1867, (2020) (PubMed).: "Characterization of a pseudoachondroplasia-associated mutation (His587-->Arg) in the C-terminal, collagen-binding domain of cartilage oligomeric matrix protein (COMP)." dans: The Biochemical journal, Vol. 377, Issue Pt 2, pp. 479-87, (2004) (PubMed).
Pseudonymes pour COMP Protéines
cartilage oligomeric matrix protein (COMP) Protéinescartilage oligomeric matrix protein (sce3551) Protéines
cartilage oligomeric matrix protein (CJA_1292) Protéines
cartilage oligomeric matrix protein (Comp) Protéines
COMP Protéines
EDM1 Protéines
EPD1 Protéines
MED Protéines
PSACH Protéines
THBS5 Protéines
TSP5 Protéines
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