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CPSF4 Produits

(Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))

Catégories

Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

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Catégories CPSF4 en vedette

CPSF4 Anticorps

High quality antibodies with extensive validation data.

CPSF4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CPSF4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7147920
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC (fro), IHC (p)
Validations
  • (2)
N° du produit ABIN1386751
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC
Validations
  • (2)
N° du produit ABIN6261007
Quantité 100 μL
Fiche technique Fiche technique

CPSF4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350238
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3078096
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3125158
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CPSF4

Li, Noah, Noah: "Alanine substitutions within a linker region of the influenza A virus non-structural protein 1 alter its subcellular localization and attenuate virus replication." dans: The Journal of general virology, Vol. 92, Issue Pt 8, pp. 1832-42, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à CPSF4

cleavage and polyadenylation specific factor 4 (CPSF4), cleavage and polyadenylation specific factor 4, 30kDa (Cpsf4), cleavage and polyadenylation specific factor 4 (LOC733099), cleavage and polyadenylation specific factor 4 (LOC100360200), cleavage and polyadenylation specific factor 4 S homeolog (cpsf4.S), cleavage and polyadenylation specific factor 4 (cpsf4), cleavage and polyadenylation specific factor 4 (Cpsf4), 30kDa, C79664, cpsf30, CPSF30, nar, NAR, neb1, NEB1

Protein level used designations for CPSF4

  • no arches
  • GLEAN_10339
  • cleavage and polyadenylation specific factor 4
  • cleavage and polyadenylation specificity factor subunit 4
  • cleavage and polyadenylation specific factor 4, 30kDa
  • CPSF 30 kDa subunit
  • cleavage and polyadenylation specific factor 4, 30kD subunit
  • cleavage and polyadenylation specificity factor 30 kDa subunit
  • clipper homolog
  • clipper/CPSF 30K
  • musculus clipper/cleavage and polyadenylation specificity factor 30 kDa subunit
  • NS1 effector domain-binding protein 1
  • cleavage-polyadenylation specificity factor, 30kD
  • neb-1
  • no arches homolog
  • no arches-like zinc finger protein
  • cleavage-polyadenylation specificity factor, 30 kD
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