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Cullin 2 Protéines

(Cullin 2 (CUL2))

Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin- conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).

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Cullin 2 Protein (CUL2) (AA 1-745) (His tag)

custom-made CUL2 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Cul2 Protein, UniprotID Q9D4H8

3 images

N° du produit ABIN7564986

Détails

Cullin 2 Protein (CUL2) (AA 1-745) (His tag)

custom-made CUL2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant CUL2 Protein, UniprotID Q13617

3 images

N° du produit ABIN7553611

Détails

Cullin 2 Protein (CUL2) (AA 1-100) (GST tag)

CUL2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP

Image no. 1 for Cullin 2 (CUL2) (AA 1-100) protein (GST tag) (ABIN1350760)

1 image

N° du produit ABIN1350760

Détails

Cullin 2 Protein (CUL2) (AA 1-745) (GST tag)

CUL2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP

Image no. 1 for Cullin 2 (CUL2) (AA 1-745) protein (GST tag) (ABIN1350758)

1 image

N° du produit ABIN1350758

Détails

Cullin 2 Protein (CUL2) (His tag)

CUL2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA

N° du produit ABIN7576436

Détails

Cullin 2 Protein (CUL2) (AA 511-745) (His tag,GST tag)

CUL2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

N° du produit ABIN7423426

Détails

Cullin 2 Protein (CUL2) (AA 1-745) (Strep Tag)

custom-made CUL2 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3137093

Détails

Cullin 2 Protein (CUL2) (AA 1-745) (Strep Tag)

custom-made CUL2 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3092033