Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Cullin 4B Produits

(Cullin 4B (CUL4B))

Catégories

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories Cullin 4B en vedette

Cullin 4B Anticorps

High quality antibodies with extensive validation data.

Cullin 4B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Cullin 4B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (6)
N° du produit ABIN3187726
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN6139255
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Dog, Human, Mouse
Application WB, IHC, IHC (p)
Validations
  • (6)
N° du produit ABIN1490724
Quantité 100 μL
Fiche technique Fiche technique

Cullin 4B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6215470
Quantité 96 tests
Fiche technique Fiche technique

Cullin 4B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350769
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3130673
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3091967
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Cullin 4B

Aggarwal, Vaites, Kim, Mellert, Gurung, Nakagawa, Herlyn, Hua, Rustgi, McMahon, Diehl: "Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase." dans: Cancer cell, Vol. 18, Issue 4, pp. 329-40, (2010) (PubMed).

Kerzendorfer, Whibley, Carpenter, Outwin, Chiang, Turner, Schwartz, El-Khamisy, Raymond, ODriscoll: "Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks." dans: Human molecular genetics, Vol. 19, Issue 7, pp. 1324-34, (2010) (PubMed).

Gascoin-Lachambre, Buffat, Rebourcet, Chelbi, Rigourd, Mondon, Mignot, Legras, Simeoni, Vaiman, Barbaux: "Cullins in human intra-uterine growth restriction: expressional and epigenetic alterations." dans: Placenta, Vol. 31, Issue 2, pp. 151-7, (2010) (PubMed).

Badura-Stronka, Jamsheer, Materna-Kiryluk, Sowińska, Kiryluk, Budny, Latos-Bieleńska: "A novel nonsense mutation in CUL4B gene in three brothers with X-linked mental retardation syndrome." dans: Clinical genetics, Vol. 77, Issue 2, pp. 141-4, (2010) (PubMed).

Abbas, Shibata, Park, Jha, Karnani, Dutta: "CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation." dans: Molecular cell, Vol. 40, Issue 1, pp. 9-21, (2010) (PubMed).

Tarpey, Raymond, OMeara, Edkins, Teague, Butler, Dicks, Stevens, Tofts, Avis, Barthorpe, Buck, Cole, Gray, Halliday, Harrison, Hills, Jenkinson, Jones, Menzies, Mironenko, Perry, Raine, Richardson et al.: "Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, ..." dans: American journal of human genetics, Vol. 80, Issue 2, pp. 345-52, (2007) (PubMed).

Zou, Liu, Chen, Zhang, Guo, Zhou, Li, Gao, Guo, Yan, Wei, Shao, Gong: "Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation." dans: American journal of human genetics, Vol. 80, Issue 3, pp. 561-6, (2007) (PubMed).

Ohtake, Baba, Takada, Okada, Iwasaki, Miki, Takahashi, Kouzmenko, Nohara, Chiba, Fujii-Kuriyama, Kato: "Dioxin receptor is a ligand-dependent E3 ubiquitin ligase." dans: Nature, Vol. 446, Issue 7135, pp. 562-6, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à Cullin 4B

cullin 4B (CUL4B), cullin 4B (Cul4b), cullin 4B (cul4b), cullin 4B S homeolog (cul4b.S), cullin 4B (Tb927.3.1290), 2700050M05Rik, AA409770, CUL-4B, im:7140950, im:7150765, MGC115611, mKIAA0695, MRXHF2, mrxhf2, MRXS15, MRXSC, mrxsc, RGD1564494, SFM2, sfm2, Tb03.1J15.620

Protein level used designations for Cullin 4B

  • CUL-4B
  • cullin-4B
  • cullin 4B
  • cullin-4B-like
Vous êtes ici:
Support technique