Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CXCR2 Produits

(Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Catégories

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories CXCR2 en vedette

CXCR2 Anticorps

High quality antibodies with extensive validation data.

CXCR2 Kits ELISA

Reliable ELISA kits for a wide range of species.

CXCR2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CXCR2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (5)
  • (4)
N° du produit ABIN732218
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (5)
N° du produit ABIN7193273
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (5)
N° du produit ABIN6256283
Quantité 100 μL
Fiche technique Fiche technique

CXCR2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965748
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962628
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954691
Quantité 96 tests
Fiche technique Fiche technique

CXCR2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350835
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1330037
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3113240
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CXCR2

Kurz, Barthelmes, Blum, Ulshöfer, Wegner, Ferreirós, Roser, Geisslinger, Grösch, Schiffmann: "Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes." dans: Scientific reports, Vol. 9, Issue 1, pp. 747, (2020) (PubMed).

Li, Zheng, Li, Zheng, Chen, Liu, Tai, Zhang, Wang, Yang: "Mesenchymal Stem Cells Ameliorate Hepatic Ischemia/Reperfusion Injury via Inhibition of Neutrophil Recruitment." dans: Journal of immunology research, Vol. 2018, pp. 7283703, (2019) (PubMed).

Zhang, Ling, Pang, Wang, Liu, Wang, Liang, Guo, Qin, Wang: "Direct Macromolecular Drug Delivery to Cerebral Ischemia Area using Neutrophil-Mediated Nanoparticles." dans: Theranostics, Vol. 7, Issue 13, pp. 3260-3275, (2018) (PubMed).

Jayatilaka, Tyle, Chen, Kwak, Ju, Kim, Lee, Wu, Gilkes, Fan, Wirtz: "Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration." dans: Nature communications, Vol. 8, pp. 15584, (2017) (PubMed).

Polat, Tunc, Erdem, Yerebasmaz, Tas, Beken, Basbozkurt, Saldir, Zenciroglu, Yaman: "Interleukin-8 and Its Receptors in Human Milk from Mothers of Full-Term and Premature Infants." dans: Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, Vol. 11, pp. 247-51, (2017) (PubMed).

Li, Duan, Yu, Dang: "NFATc1 regulates cell proliferation, migration, and invasion of ovarian cancer SKOV3 cells in vitro and in vivo." dans: Oncology reports, Vol. 36, Issue 2, pp. 918-28, (2017) (PubMed).

Alexeev, Donahue, Uitto, Igoucheva: "Chemotaxis-driven disease-site targeting of therapeutic adult stem cells in dystrophic epidermolysis bullosa." dans: Stem cell research & therapy, Vol. 7, Issue 1, pp. 124, (2016) (PubMed).

Csépányi-Kömi, Wisniewski, Bartos, Lévai, Németh, Balázs, Kurz, Bierschenk, Sperandio, Ligeti: "Rac GTPase Activating Protein ARHGAP25 Regulates Leukocyte Transendothelial Migration in Mice." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 7, pp. 2807-15, (2016) (PubMed).

Li, Huang, Foley, Xu, Li, Pan, Redmond, Wang, Wang: "B7H3 ameliorates LPS-induced acute lung injury via attenuation of neutrophil migration and infiltration." dans: Scientific reports, Vol. 6, pp. 31284, (2016) (PubMed).

Williams, José, Mercer, Brealey, Parekh, Thickett, OKane, McAuley, Chambers: "Evidence for chemokine synergy during neutrophil migration in ARDS." dans: Thorax, Vol. 72, Issue 1, pp. 66-73, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à CXCR2

C-X-C motif chemokine receptor 2 (Cxcr2), C-X-C motif chemokine receptor 2 (CXCR2), chemokine (C-X-C motif) receptor 2 (Cxcr2), CD128, CD182, CDw128, CDw128b, CMKAR2, Cmkar2, CXC-R2, CXCR-2, Gpcr16, IL-8rb, IL-8Rh, IL8R2, IL8RA, IL8RB, Il8rb, mIL-8RH

Protein level used designations for CXCR2

  • C-X-C chemokine receptor type 2
  • interleukin 8 receptor beta
  • interleukin-8 receptor CXCR2
  • CXC-R2
  • CXCR-2
  • CXCR2 gene for IL8 receptor type B
  • GRO/MGSA receptor
  • IL-8 receptor type 2
  • IL-8R B
  • chemokine (CXC) receptor 2
  • high affinity interleukin-8 receptor B
  • interleukin 8 receptor B
  • interleukin 8 receptor type 2
  • interleukin 8 receptor, beta
  • interleukin-8 receptor type B
  • chemokine receptor CXCR2
  • interleukin 8 receptor, alpha
  • IL-8 receptor alpha chain
  • chemokine (C-X-C) receptor 2
  • IL-8 receptor
  • High affinity interleukin-8 receptor B
  • interleukin-8 receptor, beta
Vous êtes ici:
Support technique