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CYP2E1 Produits

(Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))

Catégories

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [provided by RefSeq, Jul 2008].

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Catégories CYP2E1 en vedette

CYP2E1 Anticorps

High quality antibodies with extensive validation data.

CYP2E1 Kits ELISA

Reliable ELISA kits for a wide range of species.

CYP2E1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CYP2E1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7438247
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (1)
  • (4)
N° du produit ABIN3023079
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (3)
  • (5)
N° du produit ABIN3043821
Quantité 100 μg
Fiche technique Fiche technique

CYP2E1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
N° du produit ABIN6720507
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (7)
  • (1)
N° du produit ABIN6955251
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6975637
Quantité 96 tests
Fiche technique Fiche technique

CYP2E1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122582
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350977
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1350976
Quantité 25 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CYP2E1

Kołota, Głąbska, Oczkowski, Gromadzka-Ostrowska: "Oxidative Stress Parameters in the Liver of Growing Male Rats Receiving Various Alcoholic Beverages." dans: Nutrients, Vol. 12, Issue 1, (2020) (PubMed).

Ran, Chen, Liang, Liao, Jiang, Huang, Ning, Zang, Zhou, Liao, Liu, Qin, Yang, Li, Ho, Liang, Ye: "Alcohol-induced autophagy via upregulation of PIASy promotes HCV replication in human hepatoma cells." dans: Cell death & disease, Vol. 9, Issue 9, pp. 898, (2018) (PubMed).

Iwao, Ojima, Kobayashi, Kishi, Nara, Esaki, Shimada, Hiraoka, Tanabe, Kanai: "Liver atrophy after percutaneous transhepatic portal embolization occurs in two histological phases: Hepatocellular atrophy followed by apoptosis." dans: World journal of hepatology, Vol. 9, Issue 32, pp. 1227-1238, (2017) (PubMed).

Ma, Zhu, Tan, Mao, Tang, Shen, Zhang, Kuang, Fei, Yang, Wang: "Gpr110 deficiency decelerates carcinogen-induced hepatocarcinogenesis via activation of the IL-6/STAT3 pathway." dans: American journal of cancer research, Vol. 7, Issue 3, pp. 433-447, (2017) (PubMed).

Yang, Cusimano, Monga, Preziosi, Pullara, Calero, Lang, Yamaguchi, Nejak-Bowen, Monga: "WNT5A Inhibits Hepatocyte Proliferation and Concludes ?-Catenin Signaling in Liver Regeneration." dans: The American journal of pathology, Vol. 185, Issue 8, pp. 2194-205, (2015) (PubMed).

Possamai, McPhail, Khamri, Wu, Concas, Harrison, Williams, Cox, Cox, Anstee, Thursz: "The role of intestinal microbiota in murine models of acetaminophen-induced hepatotoxicity." dans: Liver international : official journal of the International Association for the Study of the Liver, (2014) (PubMed).

Kadir, Kassim, Abdulla, Kamalidehghan, Ahmadipour, Yehye: "PASS-predicted hepatoprotective activity of Caesalpinia sappan in thioacetamide-induced liver fibrosis in rats." dans: TheScientificWorldJournal, Vol. 2014, pp. 301879, (2014) (PubMed).

Jiang, Fan, Wang, Chen, Zeng, Tan, Gonzalez, Huang, Bi: "Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 143, Issue 1, pp. 107-15, (2014) (PubMed).

Fan, Jiang, Wang, Tan, Zeng, Wang, Chen, Qu, Gonzalez, Huang, Bi: "Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 42, Issue 12, pp. 1982-90, (2014) (PubMed).

Fagerberg, Hallström, Oksvold, Kampf, Djureinovic, Odeberg, Habuka, Tahmasebpoor, Danielsson, Edlund, Asplund, Sjöstedt, Lundberg, Szigyarto, Skogs, Takanen, Berling, Tegel, Mulder, Nilsson, Schwenk et al.: "Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. ..." dans: Molecular & cellular proteomics : MCP, Vol. 13, Issue 2, pp. 397-406, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à CYP2E1

cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1), cytochrome P450 2E1 (CYP2E1), cytochrome P450 2E1 (PTRG_07411), cytochrome P450 2E1 (LOC100342572), cytochrome P450 2E1 (LOC100727914), cytochrome P450 2E1-like (LOC101843716), cytochrome P450 family 2 subfamily E member 1 (CYP2E1), cytochrome P450, family 2, subfamily e, polypeptide 1 (Cyp2e1), CPE1, CYP2E, Cyp2e, CYP2E1, CYPIIE1, P450-J, P450C2E

Protein level used designations for CYP2E1

  • cytochrome P450 2E1
  • 4-nitrophenol 2-hydroxylase
  • Cytochrome P450 2E1
  • Cytochrome P450 LM3A
  • Cytochrome P450 isozyme 3A
  • Cytochrome P450-ALC
  • Cytochrome P450-J
  • cytochrome P-450j
  • CYPIIE1
  • cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1
  • cytochrome P450-J
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • xenobiotic monooxygenase
  • cytochrome P450, 2e1, ethanol inducible
  • cytochrome P450-ALC
  • P450-J
  • P450RLM6
  • cytochrome P450 subfamily 2e1 (ethanol-inducible)
  • cytochrome P450, subfamily 2E, polypeptide 1
  • cytochrome P450RLM6
  • cytochrome P-450-J
  • cytochrome P450 CYP2E1
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