CYP3A5 Produits
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
Catégories
This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2010].
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Catégories CYP3A5 en vedette
CYP3A5 Anticorps
High quality antibodies with extensive validation data.
CYP3A5 Kits ELISA
Reliable ELISA kits for a wide range of species.
CYP3A5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CYP3A5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7149265
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
N° du produit
ABIN652394
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), IF
Validations
- (4)
N° du produit
ABIN392224
Quantité
400 μL
Fiche technique
Fiche technique
CYP3A5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966252
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955260
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN2946890
Quantité
96 tests
Fiche technique
Fiche technique
CYP3A5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350994
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3078139
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2712776
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CYP3A5
: "Cytochrome P450 3A5 plays a prominent role in the oxidative metabolism of the anti-human immunodeficiency virus drug maraviroc." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 12, pp. 2221-30, (2012) (PubMed).: "Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects." dans: Journal of clinical pharmacology, Vol. 47, Issue 1, pp. 87-93, (2006) (PubMed).
: "Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethylation." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 33, Issue 7, pp. 1074-81, (2005) (PubMed).
: "Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 10, pp. 3758-65, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à CYP3A5
cytochrome P450 family 3 subfamily A member 5 (CYP3A5), CP35, CYPIIIA5, P450PCN3, PCN3Protein level used designations for CYP3A5
- cytochrome P450 3A5
- aryl hydrocarbon hydroxylase
- cytochrome P450 HLp2
- cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5
- cytochrome P450-PCN3
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- xenobiotic monooxygenase
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