DAAM1 Produits
(Dishevelled Associated Activator of Morphogenesis 1 (DAAM1))
Catégories
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. This protein also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2012].
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Catégories DAAM1 en vedette
DAAM1 Anticorps
High quality antibodies with extensive validation data.
DAAM1 Kits ELISA
Reliable ELISA kits for a wide range of species.
DAAM1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DAAM1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (5)
N° du produit
ABIN564982
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (6)
N° du produit
ABIN524909
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Hamster, Human
Application
WB, IHC (p), FACS
Validations
- (4)
N° du produit
ABIN651631
Quantité
400 μL
Fiche technique
Fiche technique
DAAM1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1129869
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1129870
Quantité
96 tests
Fiche technique
Fiche technique
DAAM1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351055
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3136248
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3092047
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits DAAM1
: "DAAM1 stabilizes epithelial junctions by restraining WAVE complex-dependent lateral membrane motility." dans: The Journal of cell biology, Vol. 215, Issue 4, pp. 559-573, (2017) (PubMed).: "DAAM is required for thin filament formation and Sarcomerogenesis during muscle development in Drosophila." dans: PLoS genetics, Vol. 10, Issue 2, pp. e1004166, (2014) (PubMed).
: "Molecular profile of endothelial invasion of three-dimensional collagen matrices: insights into angiogenic sprout induction in wound healing." dans: American journal of physiology. Cell physiology, Vol. 295, Issue 5, pp. C1215-29, (2008) (PubMed).
: "Mechanism of activation of the Formin protein Daam1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 210-5, (2008) (PubMed).
: "Daam1 regulates the endocytosis of EphB during the convergent extension of the zebrafish notochord." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 16, pp. 6708-13, (2007) (PubMed).
: "Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly." dans: Journal of molecular biology, Vol. 369, Issue 5, pp. 1258-69, (2007) (PubMed).
: "Crystal structure of human DAAM1 formin homology 2 domain." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 12, Issue 11, pp. 1255-65, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à DAAM1
dishevelled associated activator of morphogenesis 1 (DAAM1), dishevelled associated activator of morphogenesis 1 (Daam1), dishevelled associated activator of morphogenesis 1 S homeolog (daam1.S), dishevelled associated activator of morphogenesis 1a (daam1a), dishevelled associated activator of morphogenesis 1 (daam1), dishevelled associated activator of morphogenesis 1b (daam1b), 1700066F09Rik, 2310028E21Rik, AI503486, daam-1, daam1, DAAM1, daam1l, DKFZp468D0524, E130308H01, fc83b10, mKIAA0666, si:ch211-87i20.1, wu:fc83b10, xdaam1Protein level used designations for DAAM1
- disheveled-associated activator of morphogenesis 1
- dishevelled associated activator of morphogenesis 1
- dishevelled-associated activator of morphogenesis 1
- disheveled-associated activator of morphogenesis 1-like
- dishevelled associated activator of morphogenesis 1, like
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