DIABLO Produits
(Second Mitochondria-Derived Activator of Caspase (DIABLO))
Catégories
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq, Dec 2008].
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Catégories DIABLO en vedette
DIABLO Anticorps
High quality antibodies with extensive validation data.
DIABLO Kits ELISA
Reliable ELISA kits for a wide range of species.
DIABLO Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DIABLO recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (1)
- (4)
N° du produit
ABIN6243156
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP
Validations
- (5)
N° du produit
ABIN3023379
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
N° du produit
ABIN7270177
Quantité
100 μL
Fiche technique
Fiche technique
DIABLO recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959278
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959279
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN625468
Quantité
96 tests
Fiche technique
Fiche technique
DIABLO recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124996
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351587
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN667710
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DIABLO
: "Mesenchymal stem cells expressing interleukin-18 inhibit breast cancer in a mouse model." dans: Oncology letters, Vol. 15, Issue 5, pp. 6265-6274, (2018) (PubMed).: "Genistein protects against Aβ25-35 induced apoptosis of PC12 cells through JNK signaling and modulation of Bcl-2 family messengers." dans: BMC neuroscience, Vol. 18, Issue 1, pp. 12, (2017) (PubMed).
: "Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome." dans: Toxicology and applied pharmacology, (2016) (PubMed).
: "N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis." dans: Journal of neurochemistry, Vol. 134, Issue 5, pp. 956-68, (2015) (PubMed).
: "SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas." dans: Molecular cancer, Vol. 14, pp. 78, (2015) (PubMed).
: "A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo." dans: Molecular cancer therapeutics, Vol. 13, Issue 3, pp. 565-75, (2014) (PubMed).
: "Circulating proteolytic signatures of chemotherapy-induced cell death in humans discovered by N-terminal labeling." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 21, pp. 7594-9, (2014) (PubMed).
: "Smac/DIABLO regulates the apoptosis of hypertrophic scar fibroblasts." dans: International journal of molecular medicine, Vol. 32, Issue 3, pp. 615-22, (2013) (PubMed).
: "An apoptosis-independent role of SMAC in tumor suppression." dans: Oncogene, Vol. 32, Issue 19, pp. 2380-9, (2013) (PubMed).
: "Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis." dans: Neurobiology of disease, Vol. 55, pp. 26-35, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à DIABLO
diablo, IAP-binding mitochondrial protein (diablo), diablo, IAP-binding mitochondrial protein (Diablo), diablo IAP-binding mitochondrial protein (DIABLO), diablo, IAP-binding mitochondrial protein L homeolog (diablo.L), 0610041G12Rik, 1700006L01Rik, AU040403, DBO, DFNA64, diablo-s, smac, Smac, SMAC, smac3, XSmacProtein level used designations for DIABLO
- Direct IAP-binding protein with low pI
- diablo homolog, mitochondrial
- second mitochondria-derived activator of caspase
- direct IAP binding protein with low PI
- direct IAP-binding protein with low pI
- diablo homolog
- mitochondrial diablo-like protein
- mitochondrial diablo
- second mitochondrial derived activator of caspases
- Second mitochondria-derived activator of caspase
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