DMPK Produits
(Dystrophia Myotonica-Protein Kinase (DMPK))
Catégories
The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-37 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
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Catégories DMPK en vedette
DMPK Anticorps
High quality antibodies with extensive validation data.
DMPK Kits ELISA
Reliable ELISA kits for a wide range of species.
DMPK Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DMPK recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (6)
N° du produit
ABIN7073790
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (5)
N° du produit
ABIN950119
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
N° du produit
ABIN515032
Quantité
100 μg
Fiche technique
Fiche technique
DMPK recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5648192
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1143793
Quantité
96 tests
Fiche technique
Fiche technique
DMPK recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5569694
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351723
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3092190
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits DMPK
: "Impact of initial biofilm growth on the anode impedance of microbial fuel cells." dans: Biotechnology and bioengineering, Vol. 101, Issue 1, pp. 101-8, (2008) (PubMed).: "Myotonic dystrophy protein kinase (DMPK) induces actin cytoskeletal reorganization and apoptotic-like blebbing in lens cells." dans: Cell motility and the cytoskeleton, Vol. 45, Issue 2, pp. 133-48, (2000) (PubMed).
: "Localization of myotonic dystrophy protein kinase in human and rabbit tissues using a new panel of monoclonal antibodies." dans: Human molecular genetics, Vol. 7, Issue 12, pp. 1957-65, (1998) (PubMed).
: "Structure and genomic sequence of the myotonic dystrophy (DM kinase) gene." dans: Human molecular genetics, Vol. 2, Issue 3, pp. 299-304, (1993) (PubMed).
Synonymes et noms alternatifs relatifs à DMPK
DM1 protein kinase (DMPK), dystrophia myotonica-protein kinase (Dmpk), DM1 protein kinase (Dmpk), DM, DM1, DM1PK, Dm15, DMK, DMPK, MDPK, MT-PKProtein level used designations for DMPK
- dystrophia myotonica-protein kinase
- myotonic dystrophy protein kinase
- myotonin-protein kinase-like
- DM protein kinase
- DM-kinase
- DM1 protein kinase
- myotonic dystrophy associated protein kinase
- myotonin protein kinase A
- myotonin-protein kinase
- thymopoietin homolog
- dystrophia myotonica kinase, B15
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