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DOK1 Produits

(Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))

Catégories

The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].

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Catégories DOK1 en vedette

DOK1 Anticorps

High quality antibodies with extensive validation data.

DOK1 Kits ELISA

Reliable ELISA kits for a wide range of species.

DOK1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DOK1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN6139763
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
N° du produit ABIN7261640
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN2855104
Quantité 100 μL
Fiche technique Fiche technique

DOK1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380555
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380556
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1130511
Quantité 96 tests
Fiche technique Fiche technique

DOK1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1351900
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3079087
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3121207
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits DOK1

Sarin, Engel, Rothweiler, Cinatl, Michaelis, Frötschl, Fröhlich, Kalayda: "Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach." dans: International journal of molecular sciences, Vol. 19, Issue 3, (2018) (PubMed).

Barrett, Evans, Frolov, Britton, Pellet-Many, Yamaji, Mehta, Bandopadhyay, Li, Brandner, Zachary, Frankel: "A crucial role for DOK1 in PDGF-BB-stimulated glioma cell invasion through p130Cas and Rap1 signalling." dans: Journal of cell science, Vol. 127, Issue Pt 12, pp. 2647-58, (2014) (PubMed).

Simoncic, Bourdeau, Lee-Loy, Rohrschneider, Tremblay, Stanley, McGlade: "T-cell protein tyrosine phosphatase (Tcptp) is a negative regulator of colony-stimulating factor 1 signaling and macrophage differentiation." dans: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4149-60, (2006) (PubMed).

Yopp, Ochando, Mao, Ledgerwood, Ding, Bromberg: "Sphingosine 1-phosphate receptors regulate chemokine-driven transendothelial migration of lymph node but not splenic T cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 5, pp. 2913-24, (2005) (PubMed).

Dubé, Cheng, Tremblay: "The role of protein tyrosine phosphatase 1B in Ras signaling." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 7, pp. 1834-9, (2004) (PubMed).

Woodring, Meisenhelder, Johnson, Zhou, Field, Shah, Bladt, Pawson, Niki, Pandolfi, Wang, Hunter: "c-Abl phosphorylates Dok1 to promote filopodia during cell spreading." dans: The Journal of cell biology, Vol. 165, Issue 4, pp. 493-503, (2004) (PubMed).

Lee, Andrieu, Saltel, Destaing, Auclair, Pouchkine, Michelon, Salaun, Kobayashi, Jurdic, Kieff, Sylla: "IkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 50, pp. 17416-21, (2004) (PubMed).

Kato, Takai, Kudo: "The pre-B cell receptor signaling for apoptosis is negatively regulated by Fc gamma RIIB." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 2, pp. 629-34, (2002) (PubMed).

Liang, Wisniewski, Strife, Shivakrupa, Clarkson, Resh: "Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling." dans: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 13732-8, (2002) (PubMed).

Yamakawa, Tsuchida, Sugino: "The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors." dans: The EMBO journal, Vol. 21, Issue 7, pp. 1684-94, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à DOK1

docking protein 1 (DOK1), docking protein 1 (Dok1), docking protein 1b (dok1b), AW557123, Dok-1, dok1, P62DOK, p62DOK, zgc:76914

Protein level used designations for DOK1

  • Downstream of tyrosine kinase 1
  • docking protein 1
  • docking protein 1 (downstream of tyrosine kinase 1)
  • p62(dok)
  • pp62
  • downstream of tyrosine kinase 1
  • downstream of tyrosine kinase-1
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