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DREAM Produits

(Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Catégories

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

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Catégories DREAM en vedette

DREAM Anticorps

High quality antibodies with extensive validation data.

DREAM Kits ELISA

Reliable ELISA kits for a wide range of species.

DREAM Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DREAM recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IP
Validations
  • (5)
N° du produit ABIN565468
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6260422
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (3)
  • (3)
N° du produit ABIN544576
Quantité 400 μL
Fiche technique Fiche technique

DREAM recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380442
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951435
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1125054
Quantité 96 tests
Fiche technique Fiche technique

DREAM recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308428
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3092006
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3132716
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits DREAM

Mulholland, Spencer, Hu, Kroener, Chandler: "Neuroplasticity of A-type potassium channel complexes induced by chronic alcohol exposure enhances dendritic calcium transients in hippocampus." dans: Psychopharmacology, Vol. 232, Issue 11, pp. 1995-2006, (2015) (PubMed).

Sánchez-Aguilera, Sánchez-Alonso, Vicente-Torres, Colino: "A novel short-term plasticity of intrinsic excitability in the hippocampal CA1 pyramidal cells." dans: The Journal of physiology, Vol. 592, Issue Pt 13, pp. 2845-64, (2014) (PubMed).

Anderson, Engbers, Heath, Bartoletti, Mehaffey, Zamponi, Turner: "The Cav3-Kv4 complex acts as a calcium sensor to maintain inhibitory charge transfer during extracellular calcium fluctuations." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 18, pp. 7811-24, (2013) (PubMed).

Rainnie, Hazra, Dabrowska, Guo, Li, Dewitt, Muly: "Distribution and functional expression of Kv4 family ? subunits and associated KChIP ? subunits in the bed nucleus of the stria terminalis." dans: The Journal of comparative neurology, Vol. 522, Issue 3, pp. 609-25, (2013) (PubMed).

Fernandes, Ribeiro, Martínez, Orensanz, Barahona, Martínez-Sáenz, Recio, Benedito, Bustamante, Carballido, García-Sacristán, Prieto, Hernández: "Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck." dans: The Journal of urology, Vol. 189, Issue 4, pp. 1567-73, (2013) (PubMed).

Foeger, Norris, Wren, Nerbonne: "Augmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilization." dans: The Journal of biological chemistry, Vol. 287, Issue 12, pp. 9640-50, (2012) (PubMed).

Pruunsild, Timmusk et al.: "Subcellular localization and transcription regulatory potency of KCNIP/Calsenilin/DREAM/KChIP proteins in cultured primary cortical neurons do not provide support for their role in CRE-dependent gene ..." dans: Journal of neurochemistry, Vol. 123, Issue 1, pp. 29-43, (2012) (PubMed).

Menegola, Clark, Trimmer: "The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice." dans: Epilepsia, Vol. 53 Suppl 1, pp. 142-9, (2012) (PubMed).

Matsuyoshi, Takimoto, Yunoki, Erickson, Tyagi, Hirao, Wanaka, Yoshimura: "Distinct cellular distributions of Kv4 pore-forming and auxiliary subunits in rat dorsal root ganglion neurons." dans: Life sciences, Vol. 91, Issue 7-8, pp. 258-63, (2012) (PubMed).

Sun, Maffie, Lin, Petralia, Rudy, Hoffman: "DPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neurons." dans: Neuron, Vol. 71, Issue 6, pp. 1102-15, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à DREAM

potassium voltage-gated channel interacting protein 3 (KCNIP3), Kv channel-interacting protein 4 (LOC5568664), calsenilin (CpipJ_CPIJ002549), calsenilin (Tsp_05009), Kv channel interacting protein 3, calsenilin (Kcnip3), potassium voltage-gated channel interacting protein 3 (Kcnip3), Kv channel interacting protein 3b, calsenilin (kcnip3b), Kv channel interacting protein 3, calsenilin (KCNIP3), potassium voltage-gated channel interacting protein 3 (kcnip3), 4933407H12Rik, AI413860, CSEN, Csen, csen, DREAM, Dream, im:7145308, KCHIP3, KChIP3, kcnip3, KCNIP3, R74849, rKChIP3, zgc:73306

Protein level used designations for DREAM

  • A-type potassium channel modulatory protein 3
  • DRE-antagonist modulator
  • calsenilin
  • calsenilin, presenilin-binding protein, EF hand transcription factor
  • kv channel-interacting protein 3
  • potassium channel interacting protein 3
  • calsenilin, presenilin binding protein, EF hand transcription factor
  • A-type potassium channel modulating protein 3
  • KChIP3
  • calsenilin presenilin-binding protein EF hand transcription factor
  • calsenilin, presenilin-binding protein, EF hand transcription fa
  • downstream regulatory element-antagonist modulator
  • Kv channel interacting protein 3, calsenilin
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