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E2F1 Produits

(E2F Transcription Factor 1 (E2F1))

Catégories

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008].

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Catégories E2F1 en vedette

E2F1 Anticorps

High quality antibodies with extensive validation data.

E2F1 Kits ELISA

Reliable ELISA kits for a wide range of species.

E2F1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

E2F1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (4)
  • (6)
N° du produit ABIN969516
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS, IF
Validations
  • (5)
N° du produit ABIN7127462
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (5)
N° du produit ABIN560676
Quantité 100 μg
Fiche technique Fiche technique

E2F1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955489
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380168
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative
Validations
N° du produit ABIN773114
Quantité 96 tests
Fiche technique Fiche technique

E2F1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1352229
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3092217
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3135419
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits E2F1

Zhou, Jiang, Xia, Zhang: "Comparison of the therapeutic effects of lobaplatin and carboplatin on retinoblastoma in vitro and in vivo." dans: International journal of oncology, Vol. 57, Issue 3, pp. 697-706, (2020) (PubMed).

Sopariwala, Yadav, Badin, Likhite, Sheth, Lorca, Vila, Kim, Tong, Song, Rodney, Narkar: "Long-term PGC1β overexpression leads to apoptosis, autophagy and muscle wasting." dans: Scientific reports, Vol. 7, Issue 1, pp. 10237, (2019) (PubMed).

Zheng, Wu, Zhang, Fu, Xu, Lao, Lin, Xu: "The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45α." dans: Frontiers in oncology, Vol. 9, pp. 654, (2019) (PubMed).

Liu, Yang, Jing, Ren, Wei, Zhang, Zhang, Duan, Zhou, Sun: "Silica nanoparticle exposure inducing granulosa cell apoptosis and follicular atresia in female Balb/c mice." dans: Environmental science and pollution research international, Vol. 25, Issue 4, pp. 3423-3434, (2018) (PubMed).

Xia, Wang, Song, Meng, Huang, Huang: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." dans: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).

Singh, Dagnino: "E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair." dans: Oncotarget, Vol. 7, Issue 18, pp. 26275-92, (2018) (PubMed).

Lee, Pelletier: "Dependence of p53-deficient cells on the DHX9 DExH-box helicase." dans: Oncotarget, Vol. 8, Issue 19, pp. 30908-30921, (2017) (PubMed).

Pozner, Terooatea, Buck-Koehntop: "Cell-specific Kaiso (ZBTB33) Regulation of Cell Cycle through Cyclin D1 and Cyclin E1." dans: The Journal of biological chemistry, Vol. 291, Issue 47, pp. 24538-24550, (2017) (PubMed).

Zhang, Lu, Liu, Cui, Wang: "Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer's disease." dans: Aging, Vol. 8, Issue 2, pp. 272-90, (2016) (PubMed).

Liu, Zhang, Lan, Wang, Mou, Shao, Liu, Yang, Lin, Lin, Ji: "GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways." dans: International journal of molecular sciences, Vol. 16, Issue 9, pp. 21897-910, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à E2F1

E2F transcription factor 1 (E2f1), E2F transcription factor 1 (E2F1), E2F transcription factor 1 L homeolog (e2f1.L), ATE2FB, CG6376, dE2F, dE2f, dE2F1, dE2f1, de2f1, def21, DmE2F-1, Dmel\\CG6376, Dp, drosE2F1, DRTF1/E2F, E(Sev-CycE)3A, E(var)3-93E, E(var)3-95E, E(var)93E, E2F, e2f, E2F-1, E2F1, E2f1, e2f1, E2FB, E2FB TRANSCRIPTION FACTOR, E2F TRANSCRIPTION FACTOR-1 E2F1, E2F transcription factor 1, Evar(3)164, l(3)07172, l(3)j3B1, l(3)j3C2, l(3)rM729, mKIAA4009, RBAP1, RBBP3, RBP3, xE2F

Protein level used designations for E2F1

  • CG6376-PA
  • CG6376-PB
  • CG6376-PC
  • CG6376-PD
  • E2-promoter binding factor
  • E2f-PA
  • E2f-PB
  • E2f-PC
  • E2f-PD
  • PBR3
  • PRB-binding protein E2F-1
  • RBAP-1
  • RBBP-3
  • retinoblastoma-associated protein 1
  • retinoblastoma-binding protein 3
  • transcription factor E2F1
  • E2F-1 transcription factor
  • E2F-1
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