EBP Produits
(Emopamil Binding Protein (Sterol Isomerase) (EBP))
Catégories
The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2\; also known as Conradi-Hunermann syndrome). [provided by RefSeq, Jul 2008].
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Catégories EBP en vedette
EBP Anticorps
High quality antibodies with extensive validation data.
EBP Kits ELISA
Reliable ELISA kits for a wide range of species.
EBP Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
EBP recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (4)
N° du produit
ABIN7142288
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (3)
- (2)
N° du produit
ABIN1881278
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (3)
N° du produit
ABIN652952
Quantité
400 μL
Fiche technique
Fiche technique
EBP recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1118973
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1118974
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Validations
N° du produit
ABIN1118975
Quantité
96 tests
Fiche technique
Fiche technique
EBP recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (4)
N° du produit
ABIN3100004
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3120933
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2712409
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits EBP
: "Two novel EBP mutations in Conradi-Hünermann-Happle syndrome." dans: European journal of dermatology : EJD, Vol. 18, Issue 4, pp. 391-3, (2008) (PubMed).: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." dans: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, (2008) (PubMed).
: "Novel EBP gene mutations in Conradi-Hünermann-Happle syndrome." dans: The British journal of dermatology, Vol. 157, Issue 6, pp. 1225-9, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à EBP
emopamil binding protein (sterol isomerase) (Ebp), emopamil binding protein (sterol isomerase) L homeolog (ebp.L), emopamil binding protein (sterol isomerase) (ebp), emopamil binding protein (sterol isomerase) (EBP), phenylalkylamine Ca2+ antagonist (emopamil) binding protein (Ebp), AI255399, cdpx2, CDPX2, cho2, CHO2, cpx, CPX, cpxd, CPXD, mSI, Pabp, Td, zgc:91895Protein level used designations for EBP
- 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
- D8-D7 sterol isomerase
- emopamil-binding protein
- cholestenol Delta-isomerase
- phenylalkylamine binding protein
- delta(8)-Delta(7) sterol isomerase
- emopamil binding protein (sterol isomerase)
- 3-beta-hydroxysteroid-delta-8,delta-7-isomerase
- Chondrodysplasia punctata-2, X-linked dominant (Happle syndrome)
- emopamil-binding protein (sterol isomerase)
- sterol 8-isomerase
- phenylalkylamine Ca2+ antagonist (emopamil) binding protein
- tattered
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