EDG4 Produits
(Lysophosphatidic Acid Receptor 2 (LPAR2))
Catégories
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
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Catégories EDG4 en vedette
EDG4 Anticorps
High quality antibodies with extensive validation data.
EDG4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
EDG4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (5)
- (3)
N° du produit
ABIN390085
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC (p), ICC
Validations
- (3)
N° du produit
ABIN1910280
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (2)
N° du produit
ABIN545645
Quantité
400 μL
Fiche technique
Fiche technique
EDG4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1309684
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3118260
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3130274
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits EDG4
: "Evaluation of pancreatic cancer cell migration with multiple parameters in vitro by using an optical real-time cell mobility assay device." dans: BMC cancer, Vol. 17, Issue 1, pp. 234, (2017) (PubMed).: "LPA Induces Colon Cancer Cell Proliferation through a Cooperation between the ROCK and STAT-3 Pathways." dans: PLoS ONE, Vol. 10, Issue 9, pp. e0139094, (2015) (PubMed).
: "LPA signaling through LPA receptors regulates cellular functions of endothelial cells treated with anticancer drugs." dans: Molecular and cellular biochemistry, Vol. 408, Issue 1-2, pp. 147-54, (2015) (PubMed).
: "In vivo collective cell migration requires an LPAR2-dependent increase in tissue fluidity." dans: The Journal of cell biology, Vol. 206, Issue 1, pp. 113-27, (2014) (PubMed).
: "Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?." dans: The American journal of pathology, Vol. 181, Issue 4, pp. 1236-49, (2012) (PubMed).
: "Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture." dans: Proteomics, Vol. 10, Issue 1, pp. 141-58, (2010) (PubMed).
: "Lysophosphatidic acid induces Ca2+ mobilization and c-Myc expression in mouse embryonic stem cells via the phospholipase C pathway." dans: Cellular signalling, Vol. 21, Issue 4, pp. 523-8, (2009) (PubMed).
: "Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2." dans: Cancer research, Vol. 67, Issue 15, pp. 7238-46, (2007) (PubMed).
: "RGS18 acts as a negative regulator of osteoclastogenesis by modulating the acid-sensing OGR1/NFAT signaling pathway." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 22, Issue 10, pp. 1612-20, (2007) (PubMed).
: "Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcepsilonRI-aggregation reveals a complex network of genes involved in inflammatory responses." dans: BMC genomics, Vol. 7, pp. 210, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à EDG4
lysophosphatidic acid receptor 2 (LPAR2), lysophosphatidic acid receptor 2 S homeolog (lpar2.S), G protein-coupled bile acid receptor 1 (GPBAR1), lysophosphatidic acid receptor 2 (Lpar2), growth hormone releasing hormone receptor (GHRHR), lysophosphatidic acid receptor 2a (lpar2a), EDG-4, EDG4, Edg4, Gpbar1, IPA2, LPA-2, LPA2, lpa2, Pbx4, RGD1561336, zgc:101053Protein level used designations for EDG4
- G protein-coupled receptor
- LPA receptor 2
- LPA receptor EDG4
- endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4
- lysophosphatidic acid receptor EDG4
- lysophosphatidic acid receptor Edg-4
- G-protein coupled bile acid receptor 1
- LPA-2
- endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4
- GHRF receptor
- GHRH receptor
- GRF receptor
- growth hormone-releasing hormone receptor
- pituitary growth hormone releasing hormone receptor
- pre-B-cell leukemia transcription factor 4
- lysophosphatidic acid receptor 2
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