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FGA Produits

(Fibrinogen alpha Chain (FGA))

Catégories

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus. [provided by RefSeq, Jul 2008].

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Catégories FGA en vedette

FGA Anticorps

High quality antibodies with extensive validation data.

FGA Kits ELISA

Reliable ELISA kits for a wide range of species.

FGA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FGA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
  • (5)
N° du produit ABIN7433189
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Cow
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7443677
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IP, PLA
Validations
  • (5)
N° du produit ABIN515603
Quantité 100 μg
Fiche technique Fiche technique

FGA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
N° du produit ABIN6574256
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955777
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966736
Quantité 96 tests
Fiche technique Fiche technique

FGA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1353978
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
N° du produit ABIN3131128
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7505430
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits FGA

Shen, Zhao, Chen, Zhang, Chen, Lin, Li, Iqbal, Zhao, Liang, Wei, Feng: "Comparative Proteomics Analysis of Serum Proteins in Gestational Diabetes during Early and Middle Stages of Pregnancy." dans: Proteomics. Clinical applications, Vol. 13, Issue 5, pp. e1800060, (2020) (PubMed).

Wu, Wang, Zhang, Xu, Chen, Duan, Zhang, Wang, Zhang: "Breaking the vicious loop between inflammation, oxidative stress and coagulation, a novel anti-thrombus insight of nattokinase by inhibiting LPS-induced inflammation and oxidative stress." dans: Redox biology, Vol. 32, pp. 101500, (2020) (PubMed).

Wu, Wang, Li, Zhang, Liu, Xu, Chen, Duan, Zhang: "Nattokinase-heparin exhibits beneficial efficacy and safety-an optimal strategy for CKD patients on hemodialysis." dans: Glycoconjugate journal, Vol. 36, Issue 2, pp. 93-101, (2019) (PubMed).

Matsumoto, Matsuura, Aoki, Maehashi, Iwamoto, Ohkawa, Yoshida, Yanaga, Takada: "An efficient system for secretory production of fibrinogen using a hepatocellular carcinoma cell line." dans: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 45, Issue 3, pp. 315-25, (2016) (PubMed).

Imamura, Yamada, Tsuboi, Nakane, Tsukasaki, Komatsuzaki, Jin: "Near-Infrared Emitting PbS Quantum Dots for in Vivo Fluorescence Imaging of the Thrombotic State in Septic Mouse Brain." dans: Molecules (Basel, Switzerland), Vol. 21, Issue 8, (2016) (PubMed).

Li, He, Di, Yan, Zhang: "Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice." dans: Life sciences, Vol. 167, pp. 57-66, (2016) (PubMed).

Lin, Cong, Zhang: "Dispersing carbon nanotubes by chiral network surfactants." dans: ACS applied materials & interfaces, Vol. 7, Issue 12, pp. 6724-32, (2015) (PubMed).

Zeng, Liu, Wang, Wang, Weng, Chen, Yang: "Cocktail blood biomarkers: prediction of clinical outcomes in patients with acute ischemic stroke." dans: European neurology, Vol. 69, Issue 2, pp. 68-75, (2013) (PubMed).

Zeng, He, Liu, Wang, Weng, Wang, Chen, Yang: "Differences of circulating inflammatory markers between large- and small vessel disease in patients with acute ischemic stroke." dans: International journal of medical sciences, Vol. 10, Issue 10, pp. 1399-405, (2013) (PubMed).

Prieto-García, Zheng, Adachi, Xing, Lane, Chung, Anderson, Hansbro, Castells, Stevens: "Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen." dans: The Journal of biological chemistry, Vol. 287, Issue 11, pp. 7834-44, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à FGA

fibrinogen alpha chain (FGA), fibrinogen alpha chain (Fga), fibrinogen alpha chain (LOC698244), Ac1873, ENSMUSG00000059807, Fba5e, Fib, Fib2

Protein level used designations for FGA

  • fibrinogen alpha chain
  • fibrinogen alpha chain-like
  • fibrinogen, A alpha polypeptide
  • fibrinogen A-alpha chain
  • fibrinogen, alpha polypeptide
  • carboxy-terminal region
  • fibrinogen A-alpha-chain
  • fibrinogen alpha subunit
  • fibrinogen alpha-E subunit
  • pre-fibrinogen alpha subunit
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