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FNTA Produits

(Farnesyltransferase, CAAX Box, alpha (FNTA))

Catégories

Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010].

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Catégories FNTA en vedette

FNTA Anticorps

High quality antibodies with extensive validation data.

FNTA Kits ELISA

Reliable ELISA kits for a wide range of species.

FNTA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FNTA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (3)
N° du produit ABIN7441346
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (5)
  • (2)
N° du produit ABIN1882083
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN947877
Quantité 50 μg
Fiche technique Fiche technique

FNTA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955698
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
  • (2)
N° du produit ABIN1133744
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Various Species
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN5594906
Quantité 96 tests
Fiche technique Fiche technique

FNTA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1354288
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3080227
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3122911
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits FNTA

Lin, Shen, Hsu, Lin: "A High-Fructose-High-Coconut Oil Diet Induces Dysregulating Expressions of Hippocampal Leptin and Stearoyl-CoA Desaturase, and Spatial Memory Deficits in Rats." dans: Nutrients, Vol. 9, Issue 6, (2018) (PubMed).

Amin, Asaad, Abdel Salam, El-Abhar, Arbid et al.: "Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, Tyrosine kinase, PI3K, glucose transporters, sRAGE and visfatin in insulin ..." dans: PLoS ONE, Vol. 9, Issue 2, pp. e89169, (2014) (PubMed).

Chiba, Sato, Misawa: "Upregulation of geranylgeranyltransferase I in bronchial smooth muscle of mouse experimental asthma: its inhibition by lovastatin." dans: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, Vol. 46, Issue 1, pp. 57-64, (2010) (PubMed).

Wang, Danielson, Li, Shah, Kim, Donahoe: "The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling." dans: Science (New York, N.Y.), Vol. 271, Issue 5252, pp. 1120-2, (1996) (PubMed).

Zhang, Diehl, Kohl, Gibbs, Giros, Casey, Omer: "cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I." dans: The Journal of biological chemistry, Vol. 269, Issue 5, pp. 3175-80, (1994) (PubMed).

Andres, Milatovich, Ozçelik, Wenzlau, Brown, Goldstein, Francke: "cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences." dans: Genomics, Vol. 18, Issue 1, pp. 105-12, (1994) (PubMed).

Omer, Kral, Diehl, Prendergast, Powers, Allen, Gibbs, Kohl: "Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases." dans: Biochemistry, Vol. 32, Issue 19, pp. 5167-76, (1993) (PubMed).

Synonymes et noms alternatifs relatifs à FNTA

farnesyltransferase A (FTA), farnesyltransferase, CAAX box, alpha (FNTA), farnesyltransferase, CAAX box, alpha (Fnta), ATFTA, FARNESYLTRANSFERASE A, farnesyltransferase A, FARNESYLTRANSFERASE SUBUNIT A, FPTA, FTA, PFAS, PFT/PGGT-IALPHA, PGGT1A, PLP, PLURIPETALA, PTAR2

Protein level used designations for FNTA

  • FTase-alpha
  • GGTase-I-alpha
  • farnesyl-protein transferase alpha-subunit
  • protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
  • protein prenyltransferase alpha subunit repeat containing 2
  • ras proteins prenyltransferase subunit alpha
  • type I protein geranyl-geranyltransferase alpha subunit
  • CAAX farnesyltransferase subunit alpha
  • type I protein geranyl-geranyltransferase subunit alpha
  • Farnesyltransferase, subunit alpha
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