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FOXN1 Produits

(Forkhead Box N1 (FOXN1))

Catégories

The protein encoded by this gene is part of the forkhead family or 'winged-helix' transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. This gene family has over 100 members, subdivided into classes (A-Q) based on phylogeny. The encoded protein is proposed to regulate development of the thymus and differentiation of keratinocytes. Mutations in this gene cause severe primary T-cell immunodeficiency and congenital alopecia. In mouse mutations of this gene underlie the phenotype of the nude mouse, which has been widely used as a model system in oncology, immunology, dermatology, and transplantation studies. In humans mutations in this gene have been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013].

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Catégories FOXN1 en vedette

FOXN1 Anticorps

High quality antibodies with extensive validation data.

FOXN1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FOXN1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (3)
N° du produit ABIN1387592
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
N° du produit ABIN7153070
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS
Validations
  • (2)
N° du produit ABIN655992
Quantité 400 μL
Fiche technique Fiche technique

FOXN1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1787167
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3135432
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3092648
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits FOXN1

Volpi, Yamazaki, Brauer, van Rooijen, Hayashida, Slavotinek, Sun Kuehn, Di Rocco, Rivolta, Bortolomai, Du, Felgentreff, Ott de Bruin, Hayashida, Freedman, Marcovecchio, Capuder, Rath, Luche, Hagedorn et al.: "EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. ..." dans: The Journal of experimental medicine, Vol. 214, Issue 3, pp. 623-637, (2017) (PubMed).

Schlake, Schorpp, Maul-Pavicic, Malashenko, Boehm: "Forkhead/winged-helix transcription factor Whn regulates hair keratin gene expression: molecular analysis of the nude skin phenotype." dans: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 217, Issue 4, pp. 368-76, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à FOXN1

forkhead box N1 (FOXN1), forkhead box N1 (foxn1), forkhead box N1 (foxN1), forkhead box protein N1 (LOC100125524), forkhead box N1 (Foxn1), D11Bhm185e, Fkh19, FKHL20, foxN, FOXN1, foxN1, foxn1, HFH-11, Hfh11, nu, nude, Rnu, RONU, WHN, Whn, whnb

Protein level used designations for FOXN1

  • forkhead box protein N1
  • forkhead box N1
  • forkhead box N protein
  • forkhead box protein N1-like
  • transcription factor Forkhead box protein N1
  • Rowett nude
  • winged helix nude
  • winged-helix nude
  • winged-helix transcription factor nude
  • HNF-3/forkhead homolog 11
  • hepatocyte nuclear factor 3 forkhead homolog 11
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