GFI1 Produits
(Growth Factor Independent 1 (GFI1))
Catégories
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].
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Catégories GFI1 en vedette
GFI1 Anticorps
High quality antibodies with extensive validation data.
GFI1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GFI1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (5)
N° du produit
ABIN561035
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7245050
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (1)
N° du produit
ABIN969174
Quantité
100 μL
Fiche technique
Fiche technique
GFI1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6222660
Quantité
96 tests
Fiche technique
Fiche technique
GFI1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1355013
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3092738
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3134645
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits GFI1
: "Transcription factor induced conversion of human fibroblasts towards the hair cell lineage." dans: PLoS ONE, Vol. 13, Issue 7, pp. e0200210, (2019) (PubMed).: "GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1." dans: Nature communications, Vol. 9, Issue 1, pp. 1418, (2018) (PubMed).
: "Single-cell analysis of mixed-lineage states leading to a binary cell fate choice." dans: Nature, Vol. 537, Issue 7622, pp. 698-702, (2017) (PubMed).
: "Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1." dans: PLoS ONE, Vol. 11, Issue 7, pp. e0160344, (2017) (PubMed).
: "Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma. ..." dans: Nature, Vol. 511, Issue 7510, pp. 428-34, (2014) (PubMed).
: "Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells." dans: The Journal of steroid biochemistry and molecular biology, Vol. 103, Issue 3-5, pp. 742-6, (2007) (PubMed).
: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." dans: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à GFI1
growth factor independent 1 (Gfi1), growth factor independent 1 transcriptional repressor (GFI1), growth factor independent 1 transcriptional repressor (Gfi1), AW495828, Gfi-1, GFI-1, GFI1, GFI1A, Pal-1, Pal1, SCN2, ZNF163Protein level used designations for GFI1
- growth factor independent protein 1
- zinc finger protein Gfi-1
- growth factor independent 1
- Growth factor independent-1
- growth factor independence-1
- zinc finger protein 163
- growth factor independence 1
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