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Glypican 3 Produits

(Glypican 3 (GPC3))
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].

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Catégories Glypican 3 en vedette

Glypican 3 Anticorps

High quality antibodies with extensive validation data.

Glypican 3 Kits ELISA

Reliable ELISA kits for a wide range of species.

Glypican 3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Glypican 3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, FACS, IHC, ELISA, ICC
Validations
  • (2)
  • (7)
N° du produit ABIN969523
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (6)
N° du produit ABIN7442228
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC, ELISA
Validations
  • (6)
N° du produit ABIN7193692
Quantité 0.1 mg
Fiche technique Fiche technique

Glypican 3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (7)
  • (1)
N° du produit ABIN6956276
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
  • (1)
N° du produit ABIN6973977
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967170
Quantité 96 tests
Fiche technique Fiche technique

Glypican 3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274774
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274772
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274775
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Glypican 3

Berman, Kelada, Gutsche, Natarajan, Swenson, Fu, Hong, Ho, Choyke, Escorcia: "In Vitro Performance of Published Glypican 3-Targeting Peptides TJ12P1 and L5 Indicates Lack of Specificity and Potency." dans: Cancer biotherapy & radiopharmaceuticals, (2019) (PubMed).

Ma, Wang, Liu, Chen, Wu, Li, Mi, Hu, Chen, Zhao: "Development and in vitro study of a bi-specific magnetic resonance imaging molecular probe for hepatocellular carcinoma." dans: World journal of gastroenterology, Vol. 25, Issue 24, pp. 3030-3043, (2019) (PubMed).

Fisher, Linder, Bentzer: "Elevated plasma glypicans are associated with organ failure in patients with infection." dans: Intensive care medicine experimental, Vol. 7, Issue 1, pp. 2, (2019) (PubMed).

Zhou, Shang, Yu, Tian: "Glypican-3: A promising biomarker for hepatocellular carcinoma diagnosis and treatment." dans: Medicinal research reviews, Vol. 38, Issue 2, pp. 741-767, (2018) (PubMed).

Han, Ma, Zhao, Zhao, Batista, Zhou, Zhou, Yang, Wang, Bi, Xia, Bai, Garkavtsev, Zhang: "Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer." dans: Oncotarget, Vol. 7, Issue 28, pp. 44406-44416, (2018) (PubMed).

Hu, Cheng, He, Wei, Wu, Meng: "Autophagy suppresses proliferation of HepG2 cells via inhibiting glypican-3/wnt/β-catenin signaling." dans: OncoTargets and therapy, Vol. 11, pp. 193-200, (2018) (PubMed).

DAvola, Villacorta-Martin, Martins-Filho, Craig, Labgaa, von Felden, Kimaada, Bonaccorso, Tabrizian, Hartmann, Sebra, Schwartz, Villanueva: "High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma." dans: Scientific reports, Vol. 8, Issue 1, pp. 11570, (2018) (PubMed).

Wang, Chen, Chen, Sun, Li, Liu: "Elevated GPC3 level promotes cell proliferation in liver cancer." dans: Oncology letters, Vol. 16, Issue 1, pp. 970-976, (2018) (PubMed).

Alyoussef, Al-Gayyar: "Cytotoxic and partial hepatoprotective activity of sodium ascorbate against hepatocellular carcinoma through inhibition of sulfatase-2 in vivo and in vitro." dans: Biomedicine & pharmacotherapy, Vol. 103, pp. 362-372, (2018) (PubMed).

Cartier, Indersie, Lesjean, Charpentier, Hooks, Ghousein, Desplat, Dugot-Senant, Trézéguet, Sagliocco, Hagedorn, Grosset: "New tumor suppressor microRNAs target glypican-3 in human liver cancer." dans: Oncotarget, Vol. 8, Issue 25, pp. 41211-41226, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à Glypican 3

glypican 3 (gpc3), glypican 3 (GPC3), glypican 3 (Gpc3), dgsx, DGSX, Glypican-3, GPC3, GTR2-2, MXR7, oci-5, OCI-5, sdys, SDYS, sgb, SGB, sgbs, SGBS, sgbs1, SGBS1

Protein level used designations for Glypican 3

  • glypican 3
  • glypican-3-like
  • glypican proteoglycan 3
  • glypican-3
  • heparan sulphate proteoglycan
  • intestinal protein OCI-5
  • secreted glypican-3
  • defective in Simpson-Golabi-Behmel overgrowth syndrome
  • proteoglycan GPC3
  • Intestinal protein OCI-5
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