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GPS2 Protéines

(G Protein Pathway Suppressor 2 (GPS2))

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008].

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GPS2 Protein (AA 1-327) (His tag)

custom-made GPS2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant GPS2 Protein, UniprotID Q13227

3 images

N° du produit ABIN7548066

Détails

GPS2 Protein (AA 1-327) (GST tag)

GPS2 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AA, AP

Image no. 1 for G Protein Pathway Suppressor 2 (GPS2) (AA 1-327) protein (GST tag) (ABIN1355661)

1 image

N° du produit ABIN1355661

Détails

GPS2 Protein (AA 1-327) (Strep Tag)

custom-made GPS2 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3080928