GUT2 Protein (AA 43-600) (His tag)
Cette protéine Recombinant GUT2 est exprimée dans Escherichia coli (E. coli).
N° du produit ABIN1001067
Aperçu rapide pour GUT2 Protein (AA 43-600) (His tag) (ABIN1001067)
Antigène
GUT2
(Mitochondrial Glycerol-3-Phosphate Dehydrogenase (GUT2))
Type de proteíne
Recombinant
Origine
Humain
Source
Escherichia coli (E. coli)
Application
Western Blotting (WB), Control (Ct)
Pureté
> 95 %
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Attributs du protein
- AA 43-600
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Purification/Conjugué
- Cette GUT2 protéine est marqué à la His tag.
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Fonction
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase (mGPD) (Western Blot Control)
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Séquence
- ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS ADCISEPVNR EPPSREAQLL TLQNTSEFDI LVIGGGATGS VQAAEEALPR IVELMGRELN WDDYKKQEQL ETARKFLY
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Attributs du produit
- recombinant mGPD comprises a 558 amino acid fragment (43-600) corresponding to the GlpA domain fragment of the mature mGPD protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).
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Agent conservateur
- Dithiothreitol (DTT)
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Précaution d'utilisation
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C
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- GUT2 (Mitochondrial Glycerol-3-Phosphate Dehydrogenase (GUT2))
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Autre désignation
- Mitochondrial Glycerol-3-Phosphate Dehydrogenase
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Sujet
- Mitochondrial glycerol-3-phosphate dehydrogenase (mGPD) is a Ca2+ -sensitive, FAD-binding protein, located on the outer surface of the inner mitochondrial membrane. mGPD catalyses the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Two isoforms have been described for mGPD. Isoform 1 comprises 727aa residues, whereas isoform 2 lacks 126aa residues of the N-terminus. Deficiency of mGPD appears to contribute to the impairment of glucose-stimulated insulin release in several animal models of non-insulin dependent diabetes mellitus.,Glycerol-3-Phosphate Dehydrogenase 2, GPD2, Glycerophosphate Dehydrognase-2 Ca(2+ ) - Responsive Mitochondrial FAD-Linked, Mitochondrial GPD, GPDM, GPD-M, GPDH-M, mtGPD, GDH2.
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Poids moléculaire
- 66.26 kDa
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UniProt
- P43304
Antigène
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