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Histone H2A Produits

(Histone H2A)
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repressive state of homeotic genes of the animal throughout development. Required for histone H3 'Lys-9' methylation and histone H4 'Lys-12' acetylation, two modifications that are essential for heterochromatin formation. Also involved in DNA double strand break (DSB) repair. Essential for early development.

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Catégories Histone H2A en vedette

Histone H2A Anticorps

High quality antibodies with extensive validation data.

Histone H2A Kits ELISA

Reliable ELISA kits for a wide range of species.

Histone H2A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Histone H2A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (7)
N° du produit ABIN7267725
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN6136140
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
N° du produit ABIN7258522
Quantité 200 μL
Fiche technique Fiche technique

Histone H2A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956582
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Competition ELISA
Validations
N° du produit ABIN2112539
Quantité 96 tests
Fiche technique Fiche technique

Histone H2A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123346
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN3126014
Quantité 1 mg
Fiche technique Fiche technique
Reactivity CHO cells
Source Insect Cells
Validations
N° du produit ABIN7126067
Quantité 0.5 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Histone H2A

Diaz, Engle, Tice, Melis, Montenegro, Rodriguez-Canales, Hanson, Emmert-Buck, Bock, Moore, Zamboni, Govindarajan, Kleiner, Farci: "Molecular Signature and Mechanisms of Hepatitis D Virus-Associated Hepatocellular Carcinoma." dans: Molecular cancer research : MCR, Vol. 16, Issue 9, pp. 1406-1419, (2018) (PubMed).

Young, Hillyer, Hokamp, Fitzpatrick, Konstantinov, Welty, Ness, Werner-Washburne, Fleming, Osley: "Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast." dans: BMC genomics, Vol. 18, Issue 1, pp. 107, (2017) (PubMed).

Xiang, Laurent, Hsu, Nachtergaele, Lu, Sheng, Xu, Chen, Ouyang, Wang, Ling, Hsu, Zou, Jambhekar, He, Shi: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." dans: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).

Zhang, Tang, Jiang, Mao: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." dans: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).

Ferrari, Bruhn, Peretti, Cassani, Carotenuto, Elgendy, Shubassi, Lucca, Bermejo, Varasi, Minucci, Longhese, Foiani: "PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response." dans: Molecular cell, Vol. 67, Issue 2, pp. 266-281.e4, (2017) (PubMed).

Baron, von Schubert, Cubizolles, Siemeister, Hitchcock, Mengel, Schröder, Fernández-Montalván, von Nussbaum, Mumberg, Nigg: "Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524." dans: eLife, Vol. 5, (2017) (PubMed).

Bekier, Mazur, Rashid, Taylor: "Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores." dans: Nature communications, Vol. 6, pp. 6775, (2015) (PubMed).

Alvarez-Saavedra, De Repentigny, Lagali, Raghu Ram, Yan, Hashem, Ivanochko, Huh, Yang, Mears, Todd, Corcoran, Bassett, Tokarew, Kokavec, Majumder, Ioshikhes, Wallace, Kothary, Meshorer, Stopka et al.: "Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation. ..." dans: Nature communications, Vol. 5, pp. 4181, (2014) (PubMed).

Jha, Strahl: "An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair." dans: Nature communications, Vol. 5, pp. 3965, (2014) (PubMed).

Fleming, Beggs, Church, Tsukihashi, Pennings: "The yeast Cyc8-Tup1 complex cooperates with Hda1p and Rpd3p histone deacetylases to robustly repress transcription of the subtelomeric FLO1 gene." dans: Biochimica et biophysica acta, Vol. 1839, Issue 11, pp. 1242-55, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à Histone H2A

Histone H2A variant (His2Av), putative histone H2A (LMJF_17_0280), histone H2A (H2AX), histone cluster 1 H2A family member F (Hist1h2af), histone H2A-like (LOC100425378), histone cluster 1, H2af (Hist1h2af), histone2A1 (his2a1), histone cluster 1, H2A, III (HIST1H2A3), histone cluster 1, H2ac (HIST1H2AC), histone H2A (h2a-A), 5499, CG5499, DDBDRAFT_0205974, DDBDRAFT_0216271, DDB_0205974, DDB_0216271, Dmel\\CG5499, gamma-H2Av, gamma-HIS2AV, gamma-His2Av, gammaH2Av, H2A, H2a-221, H2A-III, H2A.F/Z, H2a.V, H2A.X, H2A.Z, H2AV, H2Av, H2av, H2AvD, H2avD, h2AvD, H2AV_DROM, H2AX, H2AZ, HIS, His, his, His2, HIS2AV, His2AV, HIS2AVD, His2AvD, HisH2Av, Hist, HIST1H2AA, Hist2av, l(3)05146, l(3)97Dd, l(3)810, l(3)L1602, RGD1564767

Protein level used designations for Histone H2A

  • CG5499-PA
  • CG5499-PB
  • H2A variant
  • His2Av-PA
  • His2Av-PB
  • Histone-2A
  • Histone2Av
  • histone
  • histone 2A variant
  • histone H2A variant
  • histone H2Av
  • histone variant H2Av
  • histone2A
  • histone2AvD
  • histone H2A
  • Histone H2a
  • histone 1, H2af
  • histone H2A type 1-F
  • histone H2a (aa 92-128)
  • CL2029_4
  • CL2029_4(696)
  • CL2029_4_ov
  • CL2029_4b
  • H2A
  • Zm.ov5
  • p-Zm.ov5
  • H2A histone
  • histone H2A-III
  • histone H2A type 1-C
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