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HNF4A Produits

(Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Catégories

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012].

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Catégories HNF4A en vedette

HNF4A Anticorps

High quality antibodies with extensive validation data.

HNF4A Kits ELISA

Reliable ELISA kits for a wide range of species.

HNF4A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HNF4A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, RNAi
Validations
  • (2)
  • (7)
N° du produit ABIN561308
Quantité 50 μg
Fiche technique Fiche technique

Application WB
Validations
  • (4)
  • (8)
N° du produit ABIN2777514
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (5)
N° du produit ABIN6256265
Quantité 100 μL
Fiche technique Fiche technique

HNF4A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967367
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6963170
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380603
Quantité 2 x 96 tests
Fiche technique Fiche technique

HNF4A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (2)
N° du produit ABIN2722902
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306853
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306855
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HNF4A

Collins, Hapke, Aravalli, Steer: "In vitro Differentiation of Human TERT-Transfected Multi-Lineage Progenitor Cells (MLPC) into Immortalized Hepatocyte-Like Cells." dans: Hepatic medicine : evidence and research, Vol. 12, pp. 79-92, (2020) (PubMed).

Aravalli, Collins, Hapke, Crane, Steer: "Hepatic Differentiation of Marmoset Embryonic Stem Cells and Functional Characterization of ESC-Derived Hepatocyte-Like Cells." dans: Hepatic medicine : evidence and research, Vol. 12, pp. 15-27, (2020) (PubMed).

Zhang, Zhong, Sun, Sun, Zhou: "Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice." dans: Scientific reports, Vol. 7, Issue 1, pp. 8976, (2019) (PubMed).

Wei, Dai, Zhou, He, Yao, Zhao, Guo, Yang: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." dans: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).

Dai, Cai, Wu, Chen, Han: "Protocatechuic acid inhibits hepatitis B virus replication by activating ERK1/2 pathway and down-regulating HNF4α and HNF1α in vitro." dans: Life sciences, Vol. 180, pp. 68-74, (2017) (PubMed).

Groth, Kao, Briët, Stankovic: "Hepatocyte nuclear factor-4 alpha in noise-induced cochlear neuropathy." dans: Developmental neurobiology, Vol. 76, Issue 12, pp. 1374-1386, (2016) (PubMed).

Zhong, Li, Sun, Zhang, Zhang, Sun, Yin, Zhang, Zhou: "Preventing Gut Leakiness and Endotoxemia Contributes to the Protective Effect of Zinc on Alcohol-Induced Steatohepatitis in Rats." dans: The Journal of nutrition, Vol. 145, Issue 12, pp. 2690-8, (2016) (PubMed).

Bonner, Kerr-Conte, Gmyr, Queniat, Moerman, Thévenet, Beaucamps, Delalleau, Popescu, Malaisse, Sener, Deprez, Abderrahmani, Staels, Pattou: "Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion." dans: Nature medicine, Vol. 21, Issue 5, pp. 512-7, (2015) (PubMed).

Ning, Koh, Pan, Jeong: "Hepatocyte nuclear factor (HNF) 4α transactivation of cytochrome P450 (Cyp) 2d40 promoter is enhanced during pregnancy in mice." dans: Biochemical pharmacology, Vol. 94, Issue 1, pp. 46-52, (2015) (PubMed).

Simeonov, Uppal: "Direct reprogramming of human fibroblasts to hepatocyte-like cells by synthetic modified mRNAs." dans: PLoS ONE, Vol. 9, Issue 6, pp. e100134, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à HNF4A

hepatocyte nuclear factor 4 alpha (HNF4A), hepatocyte nuclear factor 4 alpha (hnf4a), Hepatocyte nuclear factor 4 (Hnf4), hepatic nuclear factor 4, alpha (Hnf4a), hepatocyte nuclear factor 4, alpha (Hnf4a), hepatocyte nuclear factor 4, alpha (hnf4a), hepatocyte nuclear factor 4 alpha S homeolog (hnf4a.S), hepatocyte nuclear factor 4 alpha (Hnf4a), CG9310, dHNF-4, dHNF4, Dmel\\CG9310, DmHNF4, fb58h09, HNF-4, Hnf-4, HNF-4(D), HNF-4alpha, Hnf-4h, HNF4, Hnf4, hnf4, HNF4A, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, Hnf4alpha, id:ibd1279, MODY, MODY1, Nr2a1, NR2A1, nr2a1, NR2A4, NR2A21, TCF, Tcf14, TCF14, wu:fb58h09

Protein level used designations for HNF4A

  • hepatocyte nuclear factor 4 alpha
  • hepatocyte nuclear factor 4, alpha
  • hepatocyte nuclear factor 4-alpha-like
  • hepatocyte nuclear factor 4-alpha
  • CG9310-PA
  • CG9310-PB
  • CG9310-PD
  • CG9310-PE
  • Hnf4-PA
  • Hnf4-PB
  • Hnf4-PD
  • Hnf4-PE
  • hepatocyte nuclear factor 4
  • hepatocyte nuclear factor 4 homologue
  • HNF-4-alpha
  • HNF4 alpha
  • HNF4alpha10
  • HNF4alpha11
  • HNF4alpha12
  • Nuclear receptor 2A1
  • TCF-14
  • nuclear receptor subfamily 2 group A member 1
  • transcription factor 14
  • transcription factor HNF-4
  • alpha transcription factor 4
  • hepatic nuclear factor 4, alpha
  • HNF4alpha10/11/12
  • hepatic nuclear factor 4 alpha
  • hepatic nuclear factor 4
  • NR2A1
  • hepatic nuclear factor 4alpha
  • nuclear receptor
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