The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2009].
custom-made
HOPX
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
HOPX
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Wahyudi, Wang, McAlpine: "Dimerization of a heat shock protein 90 inhibitor enhances inhibitory activity." dans: Organic & biomolecular chemistry, Vol. 12, Issue 5, pp. 765-73, (2014) (PubMed).
Willmer, Contu, Blatch, Edkins: "Knockdown of Hop downregulates RhoC expression, and decreases pseudopodia formation and migration in cancer cell lines." dans: Cancer letters, Vol. 328, Issue 2, pp. 252-60, (2012) (PubMed).
Pseudonymes pour HOPX Protéines
HOP homeobox (HOPX) Protéines HOP homeobox (Hopx) Protéines HOP homeobox (hopx) Protéines 1110018K11Rik Protéines 1200015P04Rik Protéines 2300002F06Rik Protéines AI848177 Protéines AW490897 Protéines CAMEO Protéines Cameo Protéines cameo Protéines GIIg15b Protéines Hdop Protéines HOD Protéines Hod Protéines hod Protéines HOP Protéines Hop Protéines hop Protéines HOPX Protéines LAGY Protéines lagy Protéines MGC147344 Protéines NECC1 Protéines necc1 Protéines OB1 Protéines Ob1 Protéines ob1 Protéines Obl Protéines SMAP31 Protéines smap31 Protéines TOTO Protéines Toto Protéines toto Protéines