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HSD17B10 Produits

(Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Catégories

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].

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Catégories HSD17B10 en vedette

HSD17B10 Anticorps

High quality antibodies with extensive validation data.

HSD17B10 Kits ELISA

Reliable ELISA kits for a wide range of species.

HSD17B10 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HSD17B10 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC, IHC (wm)
Validations
  • (8)
N° du produit ABIN2854703
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Monkey
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (7)
N° du produit ABIN1498724
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (7)
N° du produit ABIN3042460
Quantité 100 μg
Fiche technique Fiche technique

HSD17B10 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967495
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975066
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956639
Quantité 96 tests
Fiche technique Fiche technique

HSD17B10 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123386
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN666970
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307111
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HSD17B10

Kristofiková, Bocková, Hegnerová, Bartos, Klaschka, Rícný, Rípová, Homola: "Enhanced levels of mitochondrial enzyme 17beta-hydroxysteroid dehydrogenase type 10 in patients with Alzheimer disease and multiple sclerosis." dans: Molecular bioSystems, Vol. 5, Issue 10, pp. 1174-9, (2009) (PubMed).

Tilton, Haidacher, Lejeune, Zhang, Zhao, Kurosky, Brasier, Denner: "Diabetes-induced changes in the renal cortical proteome assessed with two-dimensional gel electrophoresis and mass spectrometry." dans: Proteomics, Vol. 7, Issue 10, pp. 1729-42, (2007) (PubMed).

Takuma, Yao, Huang, Xu, Chen, Luddy, Trillat, Stern, Arancio, Yan: "ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 19, Issue 6, pp. 597-8, (2005) (PubMed).

Lustbader, Cirilli, Lin, Xu, Takuma, Wang, Caspersen, Chen, Pollak, Chaney, Trinchese, Liu, Gunn-Moore, Lue, Walker, Kuppusamy, Zewier, Arancio, Stern, Yan, Wu: "ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease." dans: Science (New York, N.Y.), Vol. 304, Issue 5669, pp. 448-52, (2004) (PubMed).

Kissinger, Rejto, Pelletier, Thomson, Showalter, Abreo, Agree, Margosiak, Meng, Aust, Vanderpool, Li, Tempczyk-Russell, Villafranca: "Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics." dans: Journal of molecular biology, Vol. 342, Issue 3, pp. 943-52, (2004) (PubMed).

He, Merz, Yang, Pullakart, Mehta, Schulz, Yang: "Function of human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase in androgen metabolism." dans: Biochimica et biophysica acta, Vol. 1484, Issue 2-3, pp. 267-77, (2000) (PubMed).

He, Schulz, Yang: "A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer's disease." dans: The Journal of biological chemistry, Vol. 273, Issue 17, pp. 10741-6, (1998) (PubMed).

Synonymes et noms alternatifs relatifs à HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), hydroxysteroid (17-beta) dehydrogenase 10 (hsd17b10), hydroxysteroid 17-beta dehydrogenase 10 (HSD17B10), hydroxysteroid (17-beta) dehydrogenase 10 L homeolog (hsd17b10.L), hydroxysteroid (17-beta) dehydrogenase 10 (Hsd17b10), 17b-HSD10, 17bHSD10, abad, ABAD, Ads9, camr, CAMR, DUPXp11.22, erab, ERAB, hadh2, HADH2, Hadh2, hcd2, HCD2, hsd10, HSD17B10, im:6899159, mhbd, MHBD, mrpp2, MRPP2, mrx17, MRX17, mrx31, MRX31, mrxs10, MRXS10, schad, SCHAD, sdr5c1, SDR5C1, wu:fj61f03, zgc:101605

Protein level used designations for HSD17B10

  • hydroxysteroid (17-beta) dehydrogenase 10
  • 3-hydroxyacyl-CoA dehydrogenase type-2
  • hydroxyacyl-Coenzyme A dehydrogenase, type II
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • AB-binding alcohol dehydrogenase
  • amyloid-beta peptide binding alcohol dehydrogenase
  • endoplasmic reticulum-associated amyloid beta-peptide-binding protein
  • mitochondrial RNase P subunit 2
  • mitochondrial ribonuclease P protein 2
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2
  • short chain dehydrogenase/reductase family 5C, member 1
  • short chain type dehydrogenase/reductase XH98G2
  • 17-beta-HSD 10
  • 17-beta-hydroxysteroid dehydrogenase 10
  • 3-hydroxyacyl-CoA dehydrogenase type II
  • hydroxyacyl-Coenzyme A dehydrogenase type II
  • mitochondrial RNase P protein 2
  • type II HADH
  • amyloid beta-peptide binding protein
  • short chain L-3-hydroxyacyl-CoA dehydrogenase
  • hydroxyacyl-Coenzyme A dehydrogenase, type II hydroxyacyl-Coenzyme A
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