IL-1 beta Protéines
(Interleukin 1, beta (IL1B))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
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87 Résultats
Rockland 010-001-319-0.1
IL1B
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
97,00%
SDS
1 image
Rockland Original
IL1B
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
90 %
ELISA
1 image
IL1B
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
Purity is >98 % , as determined by Coomassie stained SDS-PAGE.
FACS
Active
Rockland 009-f01-v25-0010
Animal-Free
IL1B
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
97,00%
SDS
Rockland Original
IL1B
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
Rockland 009-f01-v25-0100
Animal-Free
IL1B
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
97,00%
SDS
Rockland Original
IL1B
Origine: Boeuf (Vache)
Hôte: Levure
Recombinant
> 90 %
ELISA
IL1B
Origine: Macaque rhésus
Hôte: Escherichia coli (E. coli)
Recombinant
>98 % as determined by SDS-PAGE and HPLC.
Func
Active
IL1B
Origine: Cheval
Hôte: Escherichia coli (E. coli)
Recombinant
>95 % as determined by SDS-PAGE and HPLC.
Func
Active
MALS verified
IL1B
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
IL1B
Origine: Cynomolgus
Hôte: Levure
Recombinant
> 90 %
ELISA
Dernières publications pour nos IL-1 beta Protéines
: "Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk." dans: Frontiers in immunology, Vol. 10, pp. 746, (2020) (PubMed).: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." dans: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).
: "Regulation of the hyperosmotic induction of aquaporin 5 and VEGF in retinal pigment epithelial cells: involvement of NFAT5." dans: Molecular vision, Vol. 21, pp. 360-77, (2015) (PubMed).
: "Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist." dans: Oncogene, Vol. 34, Issue 19, pp. 2493-504, (2015) (PubMed).
: "Activated group 3 innate lymphoid cells promote T-cell-mediated immune responses." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 35, pp. 12835-40, (2014) (PubMed).
: "Activated microglia enhance neurogenesis via trypsinogen secretion." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 21, pp. 8714-9, (2013) (PubMed).
: "Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 6143-56, (2011) (PubMed).
: "Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms." dans: Annals of neurology, Vol. 70, Issue 6, pp. 943-54, (2011) (PubMed).
: "VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways." dans: Blood, Vol. 111, Issue 7, pp. 3665-74, (2008) (PubMed).
: "Up-regulation of vascular endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 4, pp. 2507-15, (2004) (PubMed).
Pseudonymes pour IL-1 beta Protéines
interleukin 1 beta (IL1B) Protéinesinterleukin 1, beta (IL1B) Protéines
interleukin 1, beta (il1b) Protéines
interleukin 1 beta (Il1b) Protéines
IL-1 Protéines
IL-1 beta Protéines
IL-1B Protéines
Il-1b Protéines
IL-1b Protéines
IL-1BETA Protéines
IL-1beta Protéines
il1-b Protéines
IL1-BETA Protéines
IL1B Protéines
IL1beta Protéines
IL1F2 Protéines
zgc:111873 Protéines
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