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Actinomycin D

Inh 50-76-0 2-Amino-N,N'-bis(6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide

N° du produit ABIN1027831

302,50 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 7 à 10 jours ouvrables

Aperçu rapide pour Actinomycin D (ABIN1027831)

Application

Inhibition (Inh)

Chemical Name

2-Amino-N,N'-bis(6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide

Fonction

Transcription inhibitor

Attributs du produit

Transcription inhibitor.

Pureté

>98 %

Formula

C62H86N12O16

Solubility

Soluble to 50 mM in DMSO
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

5-Azacytidine
Inh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

Nicotinamide
Inh 98-92-0 Pyridine-3-carboxylic acid amide

Anacardic Acid
Inh 16611-84-0 2-Hydroxy-6-pentadecylbenzoic acid

EX-527
Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)

SAHA (Vorinostat)
Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid

Phenylbutyrate Na
Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

AS-8351
Inh 796-42-9 2-Hydroxy-1-naphthylaldehyde isonicotinolyhydrazone

Commentaires

Source: Synthetic.
Appearance: White Solid

Restrictions

For Research Use only
Format

Solid

Précaution d'utilisation

Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R26/27/28 - Very Toxic by inhalation, in contact with skin and if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin R40 - Limited evidence of a carcinogenic effect R62 - Possible risk of impaired fertility Hazard Phrases: H300 - Fatal if swallowed Precautionary Phrases: P264 -P301 + P310

Conseil sur la manipulation

Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R26/27/28 - Very Toxic by inhalation, in contact with skin and if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin R40 - Limited evidence of a carcinogenic effect R62 - Possible risk of impaired fertility Hazard Phrases: H300 - Fatal if swallowed Precautionary Phrases: P264 -P301 + P310

Stock

-20 °C
Sujet

The actinomycins are a class of polypeptide antibiotics. Actinomycin D inhibits transcription by binding DNA at the transcription initiation complex and preventing elongation by RNA polymerase. Actinomycin D has been used as a chemotherapy drug, and an antibiotic.

Poids moléculaire

1255.43

Numéro CAS

50-76-0