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Felodipine

BR, Inh 72509-76-3 Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, Plendil
N° du produit ABIN1027921
251,08 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 7 à 10 jours ouvrables

Aperçu rapide pour Felodipine (ABIN1027921)

Application

Blocking Reagent (BR), Inhibition (Inh)

Chemical Name

Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, Plendil
  • Fonction

    L-type Ca channel blocker

    Attributs du produit

    L-type Ca channel blocker.

    Pureté

    >98 % (TLC), NMR (Conforms)

    Formula

    C18H19Cl2NO4

    Solubility

    Soluble to 100 mM in ethanol and to 100 mM in DMSO
  • Commentaires

    Source: Synthetic.
    Appearance: Light Yellow Solid

    Restrictions

    For Research Use only
  • Format

    Solid

    Précaution d'utilisation

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R62 - Possible risk of impaired fertility Hazard Phrases: H302

    Conseil sur la manipulation

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes Risk Phrases: R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed R62 - Possible risk of impaired fertility Hazard Phrases: H302

    Stock

    -20 °C
  • Sujet

    Felodipine is an L-type Ca2+ channel blocker. In isolated rat ventricular myocytes, using a whole-cell patch-clamp technique, it displays a Ki of 11 nM. It is a clinically useful antihypertensive agent which attenuates the hypertrophic effect of cyclosporine on transplanted hearts.

    Poids moléculaire

    384.25

    Numéro CAS

    72509-76-3
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