Conantokin G
Aperçu rapide pour Conantokin G (ABIN1540037)
Application
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Fonction
- Conantokin G inhibits NMDA receptors
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Séquence
- Gly-Glu-Gla-Gla-Leu-Gln-Gla-Asn-Gln-Gla-Leu-Ile-Arg-Gla-Lys-Ser-Asn-NH2
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Specificité
- Conantokin G has been isolated from the venom of the cone Conus geographus. This toxin selectively inhibits NR2B subunits of N-methyl-D-aspartate (NMDA) receptor-mediated calcium influx in central nervous system neurons. Conantokin G induces sleep-like symptoms in young mice and hyperactivity in older mice (SERT).
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Restrictions
- For Research Use only
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Poids moléculaire
- 2264.23 Da
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Numéro CAS
- 93438-65-4
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