Agitoxin-2
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- Application
- Blocking Reagent (BR), Inhibition Assay (InhA)
- Fonction
- Agitoxin-2 is a potent blocker of Kv1.1 and Kv1.3 channels
- Séquence
- AA sequence: Gly-Val-Pro-Ile-Asn-Val-Ser-Cys8-Thr-Gly -Ser-Pro-Gln-Cys14-Ile-Lys-Pro-Cys18-Lys-Asp- Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys28-Met-Asn -Arg-Lys-Cys33-His-Cys35-Thr-Pro-Lys-OH Disulfide bonds: Cys8-Cys28, Cys14-Cys33, Cys18-Cys35
- Specificité
- Agitoxin-2 is a potent blocker of Kv1.1 and Kv1.3 channels
- Attributs du produit
- Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 200 pM and Kv1.1 with an IC50 value of around 140 pM. This peptide toxin was originally isolated from the venom of the Israeli scorpion L. quinquestriatus hebraeus.
- Formula
- C169H278N54O48S8
- Solubility
- water and saline buffer
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Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
RadicicolInh 12772-57-5
Geldanamycin- FITCInh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
NicotinamideInh 98-92-0 Pyridine-3-carboxylic acid amide
5-AzacytidineInh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
ResveratrolAct 501-36-0 3,4',5-Trihydroxy-trans-stilbene
PanobinostatInh 404950-80-7 (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
HPA (Hexyl-4-pentynoic acid)Inh Cell-permeable 96017-59-3 2-(2-Propynyl)octanoic acid (racemic)
EX-527Inh Cell-permeable 49843-98-3 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)
DaminozideInh 1596-84-5 1-(2,2-Dimethylhydrazide)butanedioic acid
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- Restrictions
- For Research Use only
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- Format
- Powder
- Stock
- -20 °C
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- Poids moléculaire
- 4090.89 Da
- Numéro CAS
- 168147-41-9
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